A Muscle-Centric Perspective on Intermittent Fasting - 油管上看的

油管上看到有人提這個文章，我搜了一下，他們覺得 intermittent fasting likely represents a suboptimal dietary approach to remodel skeletal muscle, which could impact the ability to maintain or enhance muscle mass and quality, especially during periods of reduced energy availability.

 https://pubmed.ncbi.nlm.nih.gov/34179054/

Muscle protein is constantly "turning over" through the breakdown of old/damaged proteins and the resynthesis of new functional proteins, the algebraic difference determining net muscle gain, maintenance, or loss. This turnover, which is sensitive to the nutritional environment, ultimately determines the mass, quality, and health of skeletal muscle over time. Intermittent fasting has become a topic of interest in the health community as an avenue to improve health and body composition primarily via caloric deficiency as well as enhanced lipolysis and fat oxidation secondary to attenuated daily insulin response. However, this approach belies the established anti-catabolic effect of insulin on skeletal muscle. More importantly, muscle protein synthesis, which is the primary regulated turnover variable in healthy humans, is stimulated by the consumption of dietary amino acids, a process that is saturated at a moderate protein intake. While limited research has explored the effect of intermittent fasting on muscle-related outcomes, we propose that infrequent meal feeding and periods of prolonged fasting characteristic of models of intermittent fasting may be counter-productive to optimizing muscle protein turnover and net muscle protein balance. The present commentary will discuss the regulation of muscle protein turnover across fasted and fed cycles and contrast it with studies exploring how dietary manipulation alters the partitioning of fat and lean body mass. It is our position that intermittent fasting likely represents a suboptimal dietary approach to remodel skeletal muscle, which could impact the ability to maintain or enhance muscle mass and quality, especially during periods of reduced energy availability.

 

所有跟帖： 

• 這個，我覺得GG和旺旺更有說服力。他們是很典型的IF但是一身是肌肉和力量。網絡各種說法都有。 -古來萬事- ♀ (0 bytes) () 10/19/2022 postreply 06:25:17

• 我直覺也是覺得IF對肌肉不友好。我玩命吃了一個月比較健康的飲食也沒增重就放棄了。IF豈不更瘦了？我對IF比較感興趣是延緩 -讓理想飛- ♀ (54 bytes) () 10/19/2022 postreply 08:00:16

• 我覺得有認真鍛煉的習慣和健康飲食的意識，接下來就是幾十年的堅持和不斷進步，雖然可能比較慢。我最佩服L94607 -fitness2022- ♀ (298 bytes) () 10/19/2022 postreply 08:37:34

• 我是相信習慣成自然。不論是養成好習慣還是改掉不良習慣都是這樣。 -古來萬事- ♀ (0 bytes) () 10/19/2022 postreply 09:00:05

• 感覺做這種間歇饑餓的，絕大多數都是比較有健康意識的，飲食其他方麵應該也很注意 -羽絨服- ♂ (0 bytes) () 10/19/2022 postreply 10:12:51

• 終於有時間找來了這篇文獻的原文。 作者是多倫多大學教PE的，寫的蠻有意思的，不過他們都是理論推測 -GoGym- ♀ (434 bytes) () 10/19/2022 postreply 10:15:42

• 讚認真。我就隻看了abstract -fitness2022- ♀ (0 bytes) () 10/19/2022 postreply 21:37:15