席琳·迪翁重獲嗓音，部分歸功於一種藥物的再利用
https://www.linkedin.com/posts/davidfajgenbaum_drugrepurposing-everycure-stiffpersonsyndrome-activity-7241876072336691202-SFon/
作者：大衛·法根鮑姆，醫學博士、工商管理碩士、理學碩士
賓夕法尼亞大學醫師科學家 | Every Cure 聯合創始人兼總裁 | 暢銷書《追尋我的治愈之路》作者
2025 TED 醫師科學家
關於大衛·法根鮑姆
醫學博士、工商管理碩士、理學碩士，是 Every Cure 的聯合創始人兼總裁，也是賓夕法尼亞大學的醫師科學家。他是賓夕法尼亞大學醫學院有史以來最年輕的終身教職人員之一。他也是暢銷書《追尋我的治愈：一位醫生將希望化為行動的競賽》（Chasing My Cure: A Doctor’s Race to Turn Hope Into Action）的作者，該書已被《阿甘正傳》製片人溫迪·芬納曼改編成電影。
席琳·迪翁重獲歌喉，部分要歸功於一種重新利用的藥物！
她被診斷出患有僵人綜合征，這是一種罕見疾病，使她失去了行走、說話和唱歌的能力。她與病魔進行了一場鼓舞人心的鬥爭。
通過高強度的物理治療和使用靜脈注射免疫球蛋白（IVIg，一種最初於1952年開發的藥物），她得以恢複部分健康。
這個使用IVIg治療僵人綜合征的有力案例，正是“萬能療法”（Every Cure）存在的意義所在——發掘更多類似的用途，確保每位患者都能從現有藥物中受益。
人類進步（編輯）1年前
我建議謹慎使用“……恢複健康”和“……她取得了顯著的康複”這兩個短語。靜脈注射免疫球蛋白（IVIg）並非SPS的治愈方法，如果給人造成它能治愈SPS的印象，那就太草率了。IVIg對她和其他SPS患者的作用是減輕症狀、延緩病情進展並增強活動能力，而不是治愈。我理解帖子的用意，但作為一名SPS患者的照護者，我陪妻子接受IVIg輸注近60次，我可以肯定地說，IVIg無疑是對抗SPS、提高生活質量的有效手段，但絕非萬能藥。
Kevin Welsh • 3rd+
David Fajgenbaum，醫學博士、工商管理碩士、理學碩士：我最近加入了一家在醫療保健領域人工智能方麵做出卓越貢獻的公司。我非常希望能與您和您的團隊交流，並分享更多信息。特別是關於我們如何創建患者的數字孿生模型——模擬每位患者獨特的生理、神經和免疫特征的虛擬模型。這些數字孿生模型可以讓您的團隊在將治療方案應用於患者之前，在虛擬環境中測試各種治療方案。請聯係 kevin@dv8.bz 或直接發送消息。謝謝！
Lauren McDermott • 3rd+
感謝您分享這些信息。靜脈注射免疫球蛋白 (IVIg) 讓我得以從僵人綜合征 (SPS) 的折磨中恢複過來。雖然它不如以前那麽有效，但仍然有助於減輕痙攣和疼痛。
Lauren McDermott
非常感謝您分享您的經曆。我很高興聽到它對您有所幫助。希望它現在也能像以前一樣有效。期待未來的治療方法。
Tara Zier • 3rd+
正如 Lauren McDermott 所提到的，許多 SPS 患者都有類似的經曆，即 IVIG 有助於減輕症狀，但隨著時間的推移，其療效會逐漸減弱。我還想強調的是，即使 SPS 患者在短時間內能夠保持高水平的競技狀態，也不意味著他們的病情已經好轉。事件發生前後的“前後”都可能非常殘酷。我對此深有體會。我們需要更好的SPS治療方法，也許它正被束之高閣。正因如此，我非常感激您所做的一切，David Fajgenbaum，醫學博士、工商管理碩士、理學碩士。謝謝您！！
Daniel Adongo博士 • 第三任及以上
主席
恭喜您！來自www.apostledanieladongo.org，他同時也是一位著作頗豐的作家，以及一位ICF認證的生活教練。我曾在我的著作《振動法則——西利塔·姆貝雷雷療愈之水（係列三）》中提到過您從危及生命的疾病中幸存下來的鼓舞人心的故事。
Celine Dion got her voice back thanks in part to a repurposed drug
https://www.linkedin.com/posts/davidfajgenbaum_drugrepurposing-everycure-stiffpersonsyndrome-activity-7241876072336691202-SFon/
By David Fajgenbaum, MD, MBA, MSc
Physician-Scientist @ UPenn | Co-Founder & President @ Every Cure | Bestselling Author, Chasing My Cure
2025 TEDPhysician-Scientist 2025 TED
About David Fajgenbaum
MD, MBA, MSc, is co-Founder & President of Every Cure and a physician-scientist at the University of Pennsylvania, where he is one of the youngest faculty members ever to receive tenure at Penn Medicine. He is also the national bestselling author of Chasing My Cure: A Doctor’s Race to Turn Hope Into Action, which is being adapted into a film by Forrest Gump producer Wendy Finerman.
Celine Dion got her voice back thanks in part to a repurposed drug!
Diagnosed with stiff person syndrome, a rare disease that took away her ability to walk, talk, and sing, she has fought an inspiring battle.
Through intense physical therapy and the use of IVIg, a repurposed drug originally developed in 1952, she was able to regain some of her health.
This powerful example of using IVIg for stiff person syndrome is exactly why Every Cure exists—to uncover more uses like this and ensure that every patient can benefit from existing medicines.
Human Progress(edited) 1y
I would caution using the phrases, "...regain her health." AND "...she was able to make a remarkable recovery." IVIg is not a cure for SPS and would be reckless to give the impression it provided her with a cure. What IVIg enabled for her, and others suffering from SPS, is a lessening of symptoms and the potential slowing of progression and the strength to perform, not a cure. I appreciate the sentiment of the post but as a care giver of someone with SPS, who's taken his wife to IVIg infusions almost 60 times, IVIg is certainly a wonderful tool, in the arsenal to fight SPS and improve quality of life, but by no means a panacea.
Kevin Welsh • 3rd+
David Fajgenbaum, MD, MBA, MSc I've recently joined a company that is doing remarkable things in Artificial General Intelligence in healthcare. I'd love to connect and show you and your team more. Particularly around how we can create a digital twin of patients—virtual models that simulate each patient's unique physiological, neurological, and immunological characteristics. These digital twins would allow your team to test various treatment scenarios in a virtual environment before applying them to the patient. Reach out to kevin@dv8.bz or connect in direct message. Thank you!
Lauren McDermott • 3rd+
Thank you for sharing this information. IVIg has kept me alive with Stiff Person Syndrome. It’s not as effective as it used to be, but it still helps with reducing spasms and pain.
Lauren McDermott
thanks so much for sharing about your experience. I’m so glad to hear that it’s helped you. Wish it was as effective now as it was before. Hopeful for future treatments.
Tara Zier • 3rd+
As Lauren McDermott mentioned, many SPS patients have a similar experience where IVIG helps reduce symptoms but loses effectiveness over time. I also want to emphasize just because someone with SPS can perform at a high level for a brief period of time doesn’t mean they are better. The “before” and “after” the event can be brutal. I can speak to this from personal experience. We need a better treatment for SPS and maybe it is sitting on a shelf. That’s why I’m grateful for all of the work you are doing David Fajgenbaum, MD, MBA, MSc. Thank you!!
Dr. Daniel Adongo • 3rd+
President
Congratulations from here at: www.apostledanieladongo.org who is ALSO an AUTHOR of many books and an ICF Certified Life Coach. I actually mention your INSPIRING story of survival from a life-threatening disease in one of my books Entitled: "The Law of Vibration - On The Healing Waters of Silita Mberere (Series III).
荒謬 免疫球蛋白治愈 Celine Dion
風蕭蕭_Frank (2026-02-13 00:44:25) 評論 (0)
席琳·迪翁重獲嗓音，部分歸功於一種藥物的再利用
https://www.linkedin.com/posts/davidfajgenbaum_drugrepurposing-everycure-stiffpersonsyndrome-activity-7241876072336691202-SFon/
作者：大衛·法根鮑姆，醫學博士、工商管理碩士、理學碩士
賓夕法尼亞大學醫師科學家 | Every Cure 聯合創始人兼總裁 | 暢銷書《追尋我的治愈之路》作者
2025 TED 醫師科學家
關於大衛·法根鮑姆
醫學博士、工商管理碩士、理學碩士，是 Every Cure 的聯合創始人兼總裁，也是賓夕法尼亞大學的醫師科學家。他是賓夕法尼亞大學醫學院有史以來最年輕的終身教職人員之一。他也是暢銷書《追尋我的治愈：一位醫生將希望化為行動的競賽》（Chasing My Cure: A Doctor’s Race to Turn Hope Into Action）的作者，該書已被《阿甘正傳》製片人溫迪·芬納曼改編成電影。
席琳·迪翁重獲歌喉，部分要歸功於一種重新利用的藥物！
她被診斷出患有僵人綜合征，這是一種罕見疾病，使她失去了行走、說話和唱歌的能力。她與病魔進行了一場鼓舞人心的鬥爭。
通過高強度的物理治療和使用靜脈注射免疫球蛋白（IVIg，一種最初於1952年開發的藥物），她得以恢複部分健康。
這個使用IVIg治療僵人綜合征的有力案例，正是“萬能療法”（Every Cure）存在的意義所在——發掘更多類似的用途，確保每位患者都能從現有藥物中受益。
人類進步（編輯）1年前
我建議謹慎使用“……恢複健康”和“……她取得了顯著的康複”這兩個短語。靜脈注射免疫球蛋白（IVIg）並非SPS的治愈方法，如果給人造成它能治愈SPS的印象，那就太草率了。IVIg對她和其他SPS患者的作用是減輕症狀、延緩病情進展並增強活動能力，而不是治愈。我理解帖子的用意，但作為一名SPS患者的照護者，我陪妻子接受IVIg輸注近60次，我可以肯定地說，IVIg無疑是對抗SPS、提高生活質量的有效手段，但絕非萬能藥。
Kevin Welsh • 3rd+
David Fajgenbaum，醫學博士、工商管理碩士、理學碩士：我最近加入了一家在醫療保健領域人工智能方麵做出卓越貢獻的公司。我非常希望能與您和您的團隊交流，並分享更多信息。特別是關於我們如何創建患者的數字孿生模型——模擬每位患者獨特的生理、神經和免疫特征的虛擬模型。這些數字孿生模型可以讓您的團隊在將治療方案應用於患者之前，在虛擬環境中測試各種治療方案。請聯係 kevin@dv8.bz 或直接發送消息。謝謝！
Lauren McDermott • 3rd+
感謝您分享這些信息。靜脈注射免疫球蛋白 (IVIg) 讓我得以從僵人綜合征 (SPS) 的折磨中恢複過來。雖然它不如以前那麽有效，但仍然有助於減輕痙攣和疼痛。
Lauren McDermott
非常感謝您分享您的經曆。我很高興聽到它對您有所幫助。希望它現在也能像以前一樣有效。期待未來的治療方法。
Tara Zier • 3rd+
正如 Lauren McDermott 所提到的，許多 SPS 患者都有類似的經曆，即 IVIG 有助於減輕症狀，但隨著時間的推移，其療效會逐漸減弱。我還想強調的是，即使 SPS 患者在短時間內能夠保持高水平的競技狀態，也不意味著他們的病情已經好轉。事件發生前後的“前後”都可能非常殘酷。我對此深有體會。我們需要更好的SPS治療方法，也許它正被束之高閣。正因如此，我非常感激您所做的一切，David Fajgenbaum，醫學博士、工商管理碩士、理學碩士。謝謝您！！
Daniel Adongo博士 • 第三任及以上
主席
恭喜您！來自www.apostledanieladongo.org，他同時也是一位著作頗豐的作家，以及一位ICF認證的生活教練。我曾在我的著作《振動法則——西利塔·姆貝雷雷療愈之水（係列三）》中提到過您從危及生命的疾病中幸存下來的鼓舞人心的故事。
Celine Dion got her voice back thanks in part to a repurposed drug
https://www.linkedin.com/posts/davidfajgenbaum_drugrepurposing-everycure-stiffpersonsyndrome-activity-7241876072336691202-SFon/
By David Fajgenbaum, MD, MBA, MSc
Physician-Scientist @ UPenn | Co-Founder & President @ Every Cure | Bestselling Author, Chasing My Cure
2025 TEDPhysician-Scientist 2025 TED
About David Fajgenbaum
MD, MBA, MSc, is co-Founder & President of Every Cure and a physician-scientist at the University of Pennsylvania, where he is one of the youngest faculty members ever to receive tenure at Penn Medicine. He is also the national bestselling author of Chasing My Cure: A Doctor’s Race to Turn Hope Into Action, which is being adapted into a film by Forrest Gump producer Wendy Finerman.
Celine Dion got her voice back thanks in part to a repurposed drug!
Diagnosed with stiff person syndrome, a rare disease that took away her ability to walk, talk, and sing, she has fought an inspiring battle.
Through intense physical therapy and the use of IVIg, a repurposed drug originally developed in 1952, she was able to regain some of her health.
This powerful example of using IVIg for stiff person syndrome is exactly why Every Cure exists—to uncover more uses like this and ensure that every patient can benefit from existing medicines.
Human Progress(edited) 1y
I would caution using the phrases, "...regain her health." AND "...she was able to make a remarkable recovery." IVIg is not a cure for SPS and would be reckless to give the impression it provided her with a cure. What IVIg enabled for her, and others suffering from SPS, is a lessening of symptoms and the potential slowing of progression and the strength to perform, not a cure. I appreciate the sentiment of the post but as a care giver of someone with SPS, who's taken his wife to IVIg infusions almost 60 times, IVIg is certainly a wonderful tool, in the arsenal to fight SPS and improve quality of life, but by no means a panacea.
Kevin Welsh • 3rd+
David Fajgenbaum, MD, MBA, MSc I've recently joined a company that is doing remarkable things in Artificial General Intelligence in healthcare. I'd love to connect and show you and your team more. Particularly around how we can create a digital twin of patients—virtual models that simulate each patient's unique physiological, neurological, and immunological characteristics. These digital twins would allow your team to test various treatment scenarios in a virtual environment before applying them to the patient. Reach out to kevin@dv8.bz or connect in direct message. Thank you!
Lauren McDermott • 3rd+
Thank you for sharing this information. IVIg has kept me alive with Stiff Person Syndrome. It’s not as effective as it used to be, but it still helps with reducing spasms and pain.
Lauren McDermott
thanks so much for sharing about your experience. I’m so glad to hear that it’s helped you. Wish it was as effective now as it was before. Hopeful for future treatments.
Tara Zier • 3rd+
As Lauren McDermott mentioned, many SPS patients have a similar experience where IVIG helps reduce symptoms but loses effectiveness over time. I also want to emphasize just because someone with SPS can perform at a high level for a brief period of time doesn’t mean they are better. The “before” and “after” the event can be brutal. I can speak to this from personal experience. We need a better treatment for SPS and maybe it is sitting on a shelf. That’s why I’m grateful for all of the work you are doing David Fajgenbaum, MD, MBA, MSc. Thank you!!
Dr. Daniel Adongo • 3rd+
President
Congratulations from here at: www.apostledanieladongo.org who is ALSO an AUTHOR of many books and an ICF Certified Life Coach. I actually mention your INSPIRING story of survival from a life-threatening disease in one of my books Entitled: "The Law of Vibration - On The Healing Waters of Silita Mberere (Series III).
https://www.linkedin.com/posts/davidfajgenbaum_drugrepurposing-everycure-stiffpersonsyndrome-activity-7241876072336691202-SFon/
作者：大衛·法根鮑姆，醫學博士、工商管理碩士、理學碩士
賓夕法尼亞大學醫師科學家 | Every Cure 聯合創始人兼總裁 | 暢銷書《追尋我的治愈之路》作者
2025 TED 醫師科學家
關於大衛·法根鮑姆
醫學博士、工商管理碩士、理學碩士，是 Every Cure 的聯合創始人兼總裁，也是賓夕法尼亞大學的醫師科學家。他是賓夕法尼亞大學醫學院有史以來最年輕的終身教職人員之一。他也是暢銷書《追尋我的治愈：一位醫生將希望化為行動的競賽》（Chasing My Cure: A Doctor’s Race to Turn Hope Into Action）的作者，該書已被《阿甘正傳》製片人溫迪·芬納曼改編成電影。
席琳·迪翁重獲歌喉，部分要歸功於一種重新利用的藥物！
她被診斷出患有僵人綜合征，這是一種罕見疾病，使她失去了行走、說話和唱歌的能力。她與病魔進行了一場鼓舞人心的鬥爭。
通過高強度的物理治療和使用靜脈注射免疫球蛋白（IVIg，一種最初於1952年開發的藥物），她得以恢複部分健康。
這個使用IVIg治療僵人綜合征的有力案例，正是“萬能療法”（Every Cure）存在的意義所在——發掘更多類似的用途，確保每位患者都能從現有藥物中受益。
人類進步（編輯）1年前
我建議謹慎使用“……恢複健康”和“……她取得了顯著的康複”這兩個短語。靜脈注射免疫球蛋白（IVIg）並非SPS的治愈方法，如果給人造成它能治愈SPS的印象，那就太草率了。IVIg對她和其他SPS患者的作用是減輕症狀、延緩病情進展並增強活動能力，而不是治愈。我理解帖子的用意，但作為一名SPS患者的照護者，我陪妻子接受IVIg輸注近60次，我可以肯定地說，IVIg無疑是對抗SPS、提高生活質量的有效手段，但絕非萬能藥。
Kevin Welsh • 3rd+
David Fajgenbaum，醫學博士、工商管理碩士、理學碩士：我最近加入了一家在醫療保健領域人工智能方麵做出卓越貢獻的公司。我非常希望能與您和您的團隊交流，並分享更多信息。特別是關於我們如何創建患者的數字孿生模型——模擬每位患者獨特的生理、神經和免疫特征的虛擬模型。這些數字孿生模型可以讓您的團隊在將治療方案應用於患者之前，在虛擬環境中測試各種治療方案。請聯係 kevin@dv8.bz 或直接發送消息。謝謝！
Lauren McDermott • 3rd+
感謝您分享這些信息。靜脈注射免疫球蛋白 (IVIg) 讓我得以從僵人綜合征 (SPS) 的折磨中恢複過來。雖然它不如以前那麽有效，但仍然有助於減輕痙攣和疼痛。
Lauren McDermott
非常感謝您分享您的經曆。我很高興聽到它對您有所幫助。希望它現在也能像以前一樣有效。期待未來的治療方法。
Tara Zier • 3rd+
正如 Lauren McDermott 所提到的，許多 SPS 患者都有類似的經曆，即 IVIG 有助於減輕症狀，但隨著時間的推移，其療效會逐漸減弱。我還想強調的是，即使 SPS 患者在短時間內能夠保持高水平的競技狀態，也不意味著他們的病情已經好轉。事件發生前後的“前後”都可能非常殘酷。我對此深有體會。我們需要更好的SPS治療方法，也許它正被束之高閣。正因如此，我非常感激您所做的一切，David Fajgenbaum，醫學博士、工商管理碩士、理學碩士。謝謝您！！
Daniel Adongo博士 • 第三任及以上
主席
恭喜您！來自www.apostledanieladongo.org，他同時也是一位著作頗豐的作家，以及一位ICF認證的生活教練。我曾在我的著作《振動法則——西利塔·姆貝雷雷療愈之水（係列三）》中提到過您從危及生命的疾病中幸存下來的鼓舞人心的故事。
Celine Dion got her voice back thanks in part to a repurposed drug
https://www.linkedin.com/posts/davidfajgenbaum_drugrepurposing-everycure-stiffpersonsyndrome-activity-7241876072336691202-SFon/
By David Fajgenbaum, MD, MBA, MSc
Physician-Scientist @ UPenn | Co-Founder & President @ Every Cure | Bestselling Author, Chasing My Cure
2025 TEDPhysician-Scientist 2025 TED
About David Fajgenbaum
MD, MBA, MSc, is co-Founder & President of Every Cure and a physician-scientist at the University of Pennsylvania, where he is one of the youngest faculty members ever to receive tenure at Penn Medicine. He is also the national bestselling author of Chasing My Cure: A Doctor’s Race to Turn Hope Into Action, which is being adapted into a film by Forrest Gump producer Wendy Finerman.
Celine Dion got her voice back thanks in part to a repurposed drug!
Diagnosed with stiff person syndrome, a rare disease that took away her ability to walk, talk, and sing, she has fought an inspiring battle.
Through intense physical therapy and the use of IVIg, a repurposed drug originally developed in 1952, she was able to regain some of her health.
This powerful example of using IVIg for stiff person syndrome is exactly why Every Cure exists—to uncover more uses like this and ensure that every patient can benefit from existing medicines.
Human Progress(edited) 1y
I would caution using the phrases, "...regain her health." AND "...she was able to make a remarkable recovery." IVIg is not a cure for SPS and would be reckless to give the impression it provided her with a cure. What IVIg enabled for her, and others suffering from SPS, is a lessening of symptoms and the potential slowing of progression and the strength to perform, not a cure. I appreciate the sentiment of the post but as a care giver of someone with SPS, who's taken his wife to IVIg infusions almost 60 times, IVIg is certainly a wonderful tool, in the arsenal to fight SPS and improve quality of life, but by no means a panacea.
Kevin Welsh • 3rd+
David Fajgenbaum, MD, MBA, MSc I've recently joined a company that is doing remarkable things in Artificial General Intelligence in healthcare. I'd love to connect and show you and your team more. Particularly around how we can create a digital twin of patients—virtual models that simulate each patient's unique physiological, neurological, and immunological characteristics. These digital twins would allow your team to test various treatment scenarios in a virtual environment before applying them to the patient. Reach out to kevin@dv8.bz or connect in direct message. Thank you!
Lauren McDermott • 3rd+
Thank you for sharing this information. IVIg has kept me alive with Stiff Person Syndrome. It’s not as effective as it used to be, but it still helps with reducing spasms and pain.
Lauren McDermott
thanks so much for sharing about your experience. I’m so glad to hear that it’s helped you. Wish it was as effective now as it was before. Hopeful for future treatments.
Tara Zier • 3rd+
As Lauren McDermott mentioned, many SPS patients have a similar experience where IVIG helps reduce symptoms but loses effectiveness over time. I also want to emphasize just because someone with SPS can perform at a high level for a brief period of time doesn’t mean they are better. The “before” and “after” the event can be brutal. I can speak to this from personal experience. We need a better treatment for SPS and maybe it is sitting on a shelf. That’s why I’m grateful for all of the work you are doing David Fajgenbaum, MD, MBA, MSc. Thank you!!
Dr. Daniel Adongo • 3rd+
President
Congratulations from here at: www.apostledanieladongo.org who is ALSO an AUTHOR of many books and an ICF Certified Life Coach. I actually mention your INSPIRING story of survival from a life-threatening disease in one of my books Entitled: "The Law of Vibration - On The Healing Waters of Silita Mberere (Series III).