貼幾張數據圖說明吸煙及環境因素對肺癌發生的影響

本文內容已被 [ 閩姑 ] 在 2015-03-01 17:14:13 編輯過。如有問題,請報告版主或論壇管理刪除.


來源:



http://www.lung.org/lung-disease/lung-cancer/resources/facts-figures/lung-cancer-fact-sheet.html

以下這張圖就是方舟子在回答鳳凰健康記者有關霧霾與肺癌發生的關係的依據:



肺癌的最大危險因素是吸煙

鳳凰健康:在視頻中,很明顯提到了霧霾和肺癌的關係,您怎麽看?

方舟子:肺癌的最大危險因素是吸煙,占90%,空氣汙染是很次要的因素,占1%。肺癌發生是很緩慢的過程,要十幾幾十年時間,不是一有危險因素就馬上得癌,所以不能把現在中國肺癌發病率上升歸為空氣汙染,更可能的因素是改革開放以來煙民數量的增加。

美國肺癌發病率的變化,與平均每個美國人吸煙量的變化,存在二、三十年的遲滯。可以推知現在中國肺癌發病率的上升,是八十年代以來中國香煙消費量上升的惡果。
......

----------------------------------------------------------------------
全文如下:


Lung Cancer Fact Sheet

 

 




Mortality

  • Lung cancer is the leading cancer killer in both men and women in the United States. In 1987, it surpassed breast cancer to become the leading cause of cancer deaths in women.1
  • Lung cancer causes more deaths than the next three most common cancers combined (colon, breast and pancreatic). An estimated 158,040 Americans are expected to die from lung cancer in 2015, accounting for approximately 27 percent of all cancer deaths.2
Leading Causes of Cancer Death
  • The number of deaths due to lung cancer has increased approximately 3.5 percent between 1999 and 2012 from 152,156 to 157,499. The number of deaths among men has reached a plateau but the number is still rising among women. In 2012, there were 86,740 deaths due to lung cancer in men and 70,759 in women.1
  • The age-adjusted death rate for lung cancer is higher for men (56.1 per 100,000 persons) than for women (36.4 per 100,000 persons). It also is higher for blacks (48.3 per 100,000 persons) compared to whites (45.6 per 100,000 persons). Black men have a far higher age-adjusted lung cancer death rate than white men, while black and white women have similar rates.1

Prevalence and Incidence

  • Approximately 402,326 Americans living today have ever been diagnosed with lung cancer.3 During 2015, an estimated 221,200 new cases of lung cancer were expected to be diagnosed, representing about 13 percent of all cancer diagnoses.2
  • The majority of living lung cancer patients have been diagnosed within the last five years. Lung cancer is mostly a disease of the elderly. In 2011, 82 percent of those living with lung cancer were 60 years of age or older.3
  • In 2011, Kentucky had the highest age-adjusted lung cancer incidence rates in both men (112.2 per 100,000) and women (79.3 per 100,000). Utah had the lowest age-adjusted cancer incidence rates in both men and women (34.5 per 100,000 and 25.0 per 100,000, respectively).4 These state-specific rates were parallel to smoking prevalence rates.
  • Lung cancer is the most common cancer worldwide, accounting for 1.8 million new cases and 1.6 million deaths in 2012.5
  • The National Institutes of Health estimate that cancer care cost the United States an overall $124.6 billion in 2010, $12.1 billion of which is due to lung cancer. Lost productivity due to early death from cancer lead to an additional $134.8 billion in 2005, $36.1 billion of which was due to lung cancer.6

Gender Differences

  • Each year more men are diagnosed with lung cancer, but more women are living with the disease. The rate of new cases in 2011 showed that men develop lung cancer more often than women (64.8 and 48.6 per 100,000 respectively).3
  • The rate of new lung cancer cases (incidence) over the past 37 years has dropped for men (28% decrease), while it has risen for women (98% increase). In 1975, rates were low for women, but rising for both men and women. In 1984, the rate of new cases for men peaked (102.1 per 100,000) and then began declining. The rate of new cases for women increased further, did not peak until 1998 (52.9 per 100,000), and has now started to decline.3

Lung Cancer Incidence Trend by Sex

Racial/Ethnic Differences

  • Blacks are more likely to develop and die from lung cancer than persons of any other racial or ethnic group. The age-adjusted lung cancer incidence rate among black men is approximately 32 percent higher than for white men, even though their overall exposure to cigarette smoke, the primary risk factor for lung cancer, is lower.3,7
  • The lung cancer incidence rate for black women is roughly equal to that of white women, despite the fact that they smoke fewer cigarettes.3,7

Survival Rates

  • The lung cancer five-year survival rate (17.8%) is lower than many other leading cancer sites, such as the colon (65.4%), breast (90.5%) and prostate (99.6%).3
  • The five-year survival rate for lung cancer is 54.0 percent for cases detected when the disease is still localized (within the lungs). However, only 15 percent of lung cancer cases are diagnosed at an early stage. For distant tumors (spread to other organs) the five-year survival rate is only 4.0 percent.3
  • Over half of people with lung cancer die within one year of being diagnosed.3

Lung Cancer Diagnosis and Survival by Stage

Smoking-Attributable Lung Cancer

  • Smoking, a main cause of small cell and non-small cell lung cancer, contributes to 80 percent and 90 percent of lung cancer deaths in women and men, respectively. Men who smoke are 23 times more likely to develop lung cancer. Women are 13 times more likely, compared to never smokers.8
  • Between 2005 and 2010, an average of 130,659 Americans (74,300 men and 56,359 women) died of smoking-attributable lung cancer each year. Exposure to secondhand smoke causes approximately 7,330 lung cancer deaths among nonsmokers every year.9
  • Nonsmokers have a 20-30 percent greater chance of developing lung cancer if they are exposed to secondhand smoke at home or work.10

Other Causes

  • It has been estimated that active smoking is responsible for close to 90 percent of lung cancer cases; radon causes 10 percent, occupational exposures to carcinogens account for approximately 9 to 15 percent and outdoor air pollution 1 to 2 percent. Because of the interactions between exposures, the combined attributable risk for lung cancer can exceed 100 percent.11
  • Exposure to radon is estimated to be the second leading cause of lung cancer, accounting for an estimated 21,000 lung cancer deaths each year (range of 8,000 to 45,000). Radon is a tasteless, colorless and odorless gas that is produced by decaying uranium and occurs naturally in soil and rock. The majority of these deaths occur among smokers since there is a greater risk for lung cancer when smokers also are exposed to radon.12
  • Lung cancer can also be caused by occupational exposures, including asbestos, uranium, and coke (an important fuel in the manufacture of iron in smelters, blast furnaces, and foundries). The combination of asbestos exposure and smoking greatly increases the risk of developing lung cancer.13
  • Nonsmoking asbes­tos workers are five times more likely to develop lung cancer than non­smokers not ex­posed to asbestos; if they also smoke, the risk factor jumps to 50 or higher.11 Environmental exposures also can increase the risk of lung cancer death.14

Lung Cancer Attributable Cases

For more information on lung cancer, please review the Lung Cancer Morbidity and Mortality Trend Report on our website at www.lung.org or call the American Lung Association at 1-800-LUNG-USA FREE (1-800-586-4872 FREE).

Sources:


1. Centers for Disease Control and Prevention. National Center for Health Statistics. CDC WONDER On-line Database, compiled from Compressed Mortality File 1999-2012 Series 20 No. 2R, 2014.
2. American Cancer Society. Cancer Facts and Figures, 2015.
3. U.S. National Institutes of Health. National Cancer Institute. SEER Cancer Statistics Review, 1975-2011.
4. U.S. National Institutes of Health. National Cancer Institute. State Cancer Profiles web tool, accessed October 6, 2014.
5. 
World Health Organization. International Agency for Research on Cancer. GLOBOCAN 2012: Estimated Cancer Incidence, Mortality and Prevalence Worldwide in 2012. Lung Cancer. Accessed November 10, 2014.
6. U.S. National Institutes of Health. National Cancer Institute. Cancer Trends Progress Report – 2011/2012 Update. Costs of Cancer Care.
7. Centers for Disease Control and Prevention. National Center for Health Statistics. National Health Interview Survey, 2010. Analysis by the American Lung Association, Research and Program Services Division using SPSS software.
8. U.S. Department of Health and Human Services. The Health Consequences of Smoking: A Report of the U.S. Surgeon General, 2004.
9. U.S. Department of Health and Human Services. The Health Consequences of Smoking—50 Years of Progress: A Report of the Surgeon General, 2014.
10. U.S. Department of Health and Human Services. The Health Consequences of Involuntary Exposure to Tobacco Smoke: A Report of the Surgeon General, 2006.
11. Alberg AJ, Samet JM. Epidemiology of Lung Cancer. Chest. 2003; 123:21-49.
12. U.S. Environmental Protection Agency. A Citizen’s Guide to Radon. January 2013.
13. U.S. Department of Health and Human Services. National Toxicology Program. 12th Report on Carcinogens (RoC). June 10, 2011.
14. Jerrett M, et al. Spatial Analysis of Air Pollution and Mortality in Los Angeles. Epidemiology. November 2005; 16(6):727-36.

*Racial and ethnic minority terminology reflects those terms used by the Centers For Disease Control.

所有跟帖: 

這是針對美國人群的統計。霧霾天到北京走走就會懷疑是否適用於中國。 -viewfinder- 給 viewfinder 發送悄悄話 viewfinder 的博客首頁 (0 bytes) () 03/01/2015 postreply 17:07:34

北京霧霾天氣是什麽時候開始?霧都倫敦煙霧事件的確令12,000人死亡,是癌症死亡嗎? -閩姑- 給 閩姑 發送悄悄話 閩姑 的博客首頁 (405 bytes) () 03/01/2015 postreply 17:26:23

是的,霧霾是個大壞蛋。但結論要有數據支持,才有說服力。 -欲千北- 給 欲千北 發送悄悄話 欲千北 的博客首頁 (0 bytes) () 03/01/2015 postreply 17:38:07

現在還沒法統計影響。我不知道柴靜的片子裏到底到說了啥。但說這種嚴重空氣汙染對肺癌隻有1%的貢獻又有什麽證據呢?是負責的態度嗎? -viewfinder- 給 viewfinder 發送悄悄話 viewfinder 的博客首頁 (0 bytes) () 03/01/2015 postreply 17:47:03

2003年發表在Chest上的研究文章---11. Alberg AJ, Samet JM. Epidemiology of L -閩姑- 給 閩姑 發送悄悄話 閩姑 的博客首頁 (432 bytes) () 03/01/2015 postreply 17:55:10

謝謝提供文獻。但現在大家關注的話題是國內的霧霾,估計這篇文章不會包括對呼吸這種空氣的Epidemiological study -viewfinder- 給 viewfinder 發送悄悄話 viewfinder 的博客首頁 (0 bytes) () 03/01/2015 postreply 18:06:31

不是我提供的~.~,是ALA製圖時的依據---白"圖"黑"據" -閩姑- 給 閩姑 發送悄悄話 閩姑 的博客首頁 (4391 bytes) () 03/01/2015 postreply 18:11:18

那估計還是米國的數據。中國這種霧霾是前所未有的,真的很難說結果會怎麽樣。也許跟以前倫敦大霧有類似之處, -viewfinder- 給 viewfinder 發送悄悄話 viewfinder 的博客首頁 (218 bytes) () 03/01/2015 postreply 18:31:06

那個1%-2%的數據來源是1981年所做的一個估計值,針對美國當時的空氣質量所做的“estimate”。 -Lily168- 給 Lily168 發送悄悄話 Lily168 的博客首頁 (0 bytes) () 03/01/2015 postreply 18:28:09

多謝幫助解讀。 -viewfinder- 給 viewfinder 發送悄悄話 viewfinder 的博客首頁 (0 bytes) () 03/01/2015 postreply 18:31:55

我想再過十年二十年,我們才能認識霧霾對中國人健康的影響 -吃與活- 給 吃與活 發送悄悄話 吃與活 的博客首頁 (262 bytes) () 03/01/2015 postreply 18:06:33

呃,火山爆發了可能會有大饑荒,大胖紙才能活下來,您還周福滿幹嘛呢:) -viewfinder- 給 viewfinder 發送悄悄話 viewfinder 的博客首頁 (0 bytes) () 03/01/2015 postreply 18:10:39

你說的也對,不過我並不認為自己那麽運氣,上次發生此事是幾億年前。那些沒經過霧霾考驗的恐龍滅絕了 -吃與活- 給 吃與活 發送悄悄話 吃與活 的博客首頁 (24 bytes) () 03/01/2015 postreply 18:17:52

吸煙調查比較容易,不吸煙或吸煙。霧霾調查較難。空中粒子不是均勻分布的 -誌在千裏- 給 誌在千裏 發送悄悄話 (2887 bytes) () 03/01/2015 postreply 21:02:08

好帖,點讚 -吃與活- 給 吃與活 發送悄悄話 吃與活 的博客首頁 (21 bytes) () 03/01/2015 postreply 17:23:22

一個人不在貌美,尤其是男生.得有基本的邏輯思維及判斷能力. -閩姑- 給 閩姑 發送悄悄話 閩姑 的博客首頁 (0 bytes) () 03/01/2015 postreply 18:02:22

能做“方粉”的人一定有邏輯清晰的頭腦,不隨波逐流的見識,經常還要有悲天憫人的情懷 -吃與活- 給 吃與活 發送悄悄話 吃與活 的博客首頁 (33 bytes) () 03/01/2015 postreply 18:31:03

方粉就方粉唄.別人給封的,免費而得,不要白不要.這年頭啥都貴~~ -閩姑- 給 閩姑 發送悄悄話 閩姑 的博客首頁 (0 bytes) () 03/01/2015 postreply 18:57:16

是啊,在美國這樣低汙染的篁環境裏,空氣汙染隻占1-2%,這種統計能適用於中國嗎? -5678910- 給 5678910 發送悄悄話 (0 bytes) () 03/01/2015 postreply 20:10:37

柴靜的視頻裏不是有一個中國的研究成果嗎,無什麽不相信呢? -5678910- 給 5678910 發送悄悄話 (0 bytes) () 03/01/2015 postreply 20:12:44

請您先登陸,再發跟帖!