大師之一謝幕,刪了。
Study notes:
Before it was possible to examine the immunoglobulin genes directly, there were two main hypotheses for the origin of this diversity. The germline theory held that there is a separate gene for each different immunoglobulin chain and that the antibody repertoire is largely inherited. In contrast, somatic diversification theories proposed that the observed repertoire is generated from a limited number of inherited V-region sequences that undergo alteration within B cells during the individual’s lifetime.
Cloning of the immunoglobulin genes revealed that elements of both theories were correct and that the DNA sequence encoding each V region is generated by rearrangements of a relatively small group of inherited gene segments. Diversity is further enhanced by the process of somatic hypermutation in mature activated B cells. Thus the somatic diversification theory was essentially correct, although the concept of multiple germline genes embodied in the germline theory also proved true.
幾位大師經常教導要多讀書
所有跟帖:
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讚一個,要的就是這種與日俱進的就是精神,不能吃老本。
-betadine-
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07/11/2014 postreply
08:48:36
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謝謝鼓勵。
-26484915-
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07/11/2014 postreply
08:57:04
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impressive! 那就是說你今天認為對的事情,明天可能就會被證明是錯的。今天你認為是錯的事情,明天可能就會被證明是正確的。
-醫者意也-
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07/11/2014 postreply
08:52:41
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科學方法:從假說到理論
-26484915-
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07/11/2014 postreply
09:19:42
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讓我告訴你一個事實,科學理論的基礎是數學, 連最基本的1+2 = 2+1都是假設。。。
-littlecat8-
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07/11/2014 postreply
09:57:46
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Really???
-26484915-
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07/11/2014 postreply
10:18:08
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請注意這是由另外的假設體係導出交換律, 與此同時, 算術公理體係也可以參考這裏 http://en.wikipedia.org/
-littlecat8-
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07/11/2014 postreply
10:41:39
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數學專家,鑒定完畢~~
-隨意-
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07/11/2014 postreply
10:44:24
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專家談不上,隻是懂一點皮毛而已。。。
-littlecat8-
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07/11/2014 postreply
10:49:37
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你好像是鑒定專家啊,你上一次那個鑒定我覺得很有水平啊,哈哈
-醫者意也-
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07/11/2014 postreply
10:52:55
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thx for noticing my finding on the couple relationship
-隨意-
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07/11/2014 postreply
11:43:34
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Can you challenge those?
-26484915-
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07/11/2014 postreply
10:50:29
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公理的意思是我們不能證明是正確,也不能證明它是錯的
-littlecat8-
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07/11/2014 postreply
10:58:51
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我忽悠什麽呢? 我告訴你吧, 這叫交換公理
-littlecat8-
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07/11/2014 postreply
10:36:00
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科學的假設是很多
-指揮家-
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07/11/2014 postreply
10:51:59
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你說的已經很接近科學的本質,即科學理論不是事實,其本質上還是假設
-littlecat8-
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07/11/2014 postreply
11:08:03
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科學理論當然是最能揭示現實世界的真理的,比如
-指揮家-
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07/11/2014 postreply
11:18:43
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我可以不迷信科學,但我可以應用科學,因為科學是我們創造的工具而已。
-littlecat8-
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07/11/2014 postreply
11:34:44
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這個扯得太遠了。比如藥品是否有效有毒,與數學公理沒有任何關係。
-26484915-
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07/12/2014 postreply
04:32:00
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是否有效是不是基於數字啊?
-littlecat8-
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07/12/2014 postreply
05:24:04
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That's where research comes in.
-26484915-
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07/11/2014 postreply
10:35:22
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To you nobody is as good as you in any area.
-26484915-
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07/11/2014 postreply
12:06:16
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湊合著看吧。
-26484915-
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07/12/2014 postreply
04:14:37
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It looks good to me. Doesn't it look good to you?
-26484915-
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07/12/2014 postreply
05:41:44
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Should be: if you ARE unable ... please write in Chinese.
-26484915-
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07/13/2014 postreply
18:07:43
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對,書多讀書再多不會做人也木價值
-隨意-
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07/11/2014 postreply
10:49:21
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Like personal attacks online?
-26484915-
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07/11/2014 postreply
10:51:07
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if not agree state your thoughts without attacking~~
-隨意-
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07/11/2014 postreply
10:53:57
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Agreed!
-26484915-
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07/11/2014 postreply
13:08:38
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讚!也請寫點自己的東西出來給網友學習科普,中文最好,期盼呀。。。.
-ME_Professor-
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07/11/2014 postreply
10:46:56
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我自己也在寫論文:用海洋能源發電,可惜,放到健壇不合適。以後開老人農場,能源問題找我。嗬嗬。
-ME_Professor-
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07/11/2014 postreply
10:59:20
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What a Hot and Sexy Topic~~
-隨意-
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07/11/2014 postreply
11:06:47
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thanks.
-ME_Professor-
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07/11/2014 postreply
11:16:23
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哇,有興趣。好。show-off 一下。原理如下:
-ME_Professor-
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07/11/2014 postreply
12:11:13
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早就有了
-houtou72-
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07/11/2014 postreply
14:05:41
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您說的對!有不同的設計版本,關鍵是成本高,如何提高效率和減低成本,還是要挖掘很久。
-ME_Professor-
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07/11/2014 postreply
14:58:35
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以後開老人農場,能源問題找我- I buy the land, you provide the energy?
-tantema-
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07/11/2014 postreply
12:37:31
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君子一言!
-ME_Professor-
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07/11/2014 postreply
15:13:16
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請2648兄寫點免疫的東西,我很想學習, 如:增加免疫力真相。
-ME_Professor-
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07/11/2014 postreply
11:23:07
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增加免疫力真相
-26484915-
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07/11/2014 postreply
11:25:38
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請曬曬讀過的中醫書,期待~~
-隨意-
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07/11/2014 postreply
11:09:28
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You first~~~
-26484915-
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07/11/2014 postreply
11:11:14
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支持曬,偶們有眼福了~
-隨意-
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07/11/2014 postreply
12:00:24
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知道你想要說明什麽,但你的筆記說明你似乎仍然沒有能切入到最關鍵的問題上。
-houtou72-
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07/11/2014 postreply
14:02:49
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What is the key in your opinion
-26484915-
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07/11/2014 postreply
14:35:13