Figure 1Sodium excretion versus composite outcome events
Cubic splines for the association between sodium excretion and composite outcome events (risk of death and major cardiovascular events), overall and by hypertension status in the four included studies (N=133?118). The analyses were adjusted for the variables in the primary model which included age, sex, ancestry (Asian vs non-Asian), body-mass index, educational level, alcohol intake, current smoking, physical activity, status with respect to diabetes mellitus, a history of cardiovascular events, treatment allocation (ramipril, telmisartan, or both, and treatment with statins, β blockers, diuretic therapy, calcium antagonist, and antidiabetes medication).
