醫諾維第一篇引用的文章是今年二月23號發表在 " Immunity "期刊上，第一作者是來自 美國西奈山伊坎醫學院的Dr Henrike Janssen， 西奈山伊坎醫學院位於紐約，在全美研究型醫學院中排名第11，Henrike Janssen 很了不起，她是個敢挑戰潮流發表不同意見的人，在Twiter上她說，I think that timing between fasting and immune challenge, as well as the length of the fast is very important. As most of the time, a blanket statement doesn’t work.大多數情況下，一攬子聲明是行不通的。 我同意DrJanssen！ 此文的第二作者來自 馬薩諸塞州總醫院和哈佛醫學院。好了，第一篇文的權威性就不用質疑了。
現在我們就來看看這篇由美國西奈山伊坎醫學院、哈佛醫學院的研究人員在" Immunity "期刊上發表的題為" Monocytes re-enter the bone marrow during fasting and alter the host response to infection "的研究論文到底說了些什麽，他們是怎麽得出這一結論的。
先來說該研究結果的要點
一，空腹時，血液循環中的單核細胞遷移到骨髓
二， 單核細胞通過空腹誘發的激素應激反應增加CXCR4
三 ，長時間禁食後重新進食導致循環中單核細胞的激增
四，長時間禁食和重新進食改變了機體對細菌感染的免疫反應
Dr Janssen和她的同事的這一結論是從兩組小老鼠實驗得來的。第一組小老鼠很幸運，在醒來後立即給吃早餐，另一組不給吃早餐，兩組小老鼠都在醒來時、四小時後、八小時後分別采集血液樣本。
The concept of eating three meals a day, consisting of breakfast, lunch, and dinner, has evolved over time and varies by culture and historical period. Here's a general overview of the history of three meals a day:
Ancient Times: In ancient civilizations such as Greece and Rome, people typically had two main meals a day. The first was a light breakfast, and the second was a larger meal later in the day, which could be referred to as lunch or dinner depending on the culture. These meals often included a variety of foods and were sometimes followed by a lighter evening snack.
Middle Ages: During the Middle Ages in Europe, the practice of eating three meals a day began to emerge among the upper classes. The first meal was a light breakfast, the second was a midday meal, and the third was dinner in the evening. This pattern gradually spread to other social classes over time.
Industrial Revolution: The Industrial Revolution in the 18th and 19th centuries brought changes to work schedules and lifestyles. With more structured working hours, people started adopting the three-meal-a-day pattern as it fit better into their daily routines.
Modern Times: In the modern era, particularly in Western cultures, the three-meal-a-day pattern became the norm for many people. Breakfast is usually eaten in the morning, followed by lunch around midday, and dinner in the evening. However, it's worth noting that eating habits can vary widely from person to person and culture to culture.
It's important to recognize that not everyone follows this three-meal pattern today. Some people may prefer to eat smaller, more frequent meals, while others may practice intermittent fasting, which involves periods of fasting and eating within a specified time window. Cultural and individual preferences, as well as lifestyle factors, continue to influence eating patterns in the modern world.
醫諾維第一篇引用的文章是今年二月23號發表在 " Immunity "期刊上，第一作者是來自 美國西奈山伊坎醫學院的Dr Henrike Janssen， 西奈山伊坎醫學院位於紐約，在全美研究型醫學院中排名第11，Henrike Janssen 很了不起，她是個敢挑戰潮流發表不同意見的人，在Twiter上她說，I think that timing between fasting and immune challenge, as well as the length of the fast is very important. As most of the time, a blanket statement doesn’t work.大多數情況下，一攬子聲明是行不通的。 我同意DrJanssen！ 此文的第二作者來自 馬薩諸塞州總醫院和哈佛醫學院。好了，第一篇文的權威性就不用質疑了。
現在我們就來看看這篇由美國西奈山伊坎醫學院、哈佛醫學院的研究人員在" Immunity "期刊上發表的題為" Monocytes re-enter the bone marrow during fasting and alter the host response to infection "的研究論文到底說了些什麽，他們是怎麽得出這一結論的。
先來說該研究結果的要點
一，空腹時，血液循環中的單核細胞遷移到骨髓
二， 單核細胞通過空腹誘發的激素應激反應增加CXCR4
三 ，長時間禁食後重新進食導致循環中單核細胞的激增
四，長時間禁食和重新進食改變了機體對細菌感染的免疫反應
Dr Janssen和她的同事的這一結論是從兩組小老鼠實驗得來的。第一組小老鼠很幸運，在醒來後立即給吃早餐，另一組不給吃早餐，兩組小老鼠都在醒來時、四小時後、八小時後分別采集血液樣本。
禁食改變白細胞分布