禦姐好,因為對DNA突變後的修複有問題,她們放療好像會導致更多腫瘤,我上麵寫的令人糊塗了,改一下。。。
https://en.wikipedia.org/wiki/Ataxia_telangiectasia
Cancer and radiosensitivity
In the absence of the ATM protein, cell-cycle check-point regulation and programmed cell death in response to DSBs are defective. The result is genomic instability which can lead to the development of cancers.[25]
Irradiation and radiomimetic compounds induce DSBs which are unable to be repaired appropriately when ATM is absent. Consequently, such agents can prove especially cytotoxic to A-T cells and people with A-T.