禦姐好，她們放療好像會導致更多腫瘤，我上麵寫的令人糊塗了，改一下。。。

來源: 誌在千裏 於 2015-11-14 21:38:25 [] [舊帖] [給我悄悄話] 閱讀數 : (947 bytes)
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回答: ATM基因者的放療效果不佳。。。。 由 禦用文人 於 2015-11-14 21:32:39

禦姐好，因為對DNA突變後的修複有問題，她們放療好像會導致更多腫瘤，我上麵寫的令人糊塗了，改一下。。。

https://en.wikipedia.org/wiki/Ataxia_telangiectasia

Cancer and radiosensitivity

In the absence of the ATM protein, cell-cycle check-point regulation and programmed cell death in response to DSBs are defective. The result is genomic instability which can lead to the development of cancers.[25]

Irradiation and radiomimetic compounds induce DSBs which are unable to be repaired appropriately when ATM is absent. Consequently, such agents can prove especially cytotoxic to A-T cells and people with A-T.

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