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Patients in the Sambucol group had "pronounced improvements" in flu symptoms after three days: Nearly 90% of patients had complete cure within two to three days. Also, the Sambucol group had no drowsiness, the downside of many flu treatments.

The placebo group didn't recover until at least day six; they also took more painkillers and nasal sprays.


It's likely that antioxidants called flavonoids -- which are contained in the extract -- stimulate the immune system, writes Thom. Also, other compounds in elderberry, called anthocyanins, have an anti-inflammatory effect; this could explain the effect on aches, pains, and fever.

Elderberry extract could be an "efficient and safe treatment" for flu symptoms in otherwise healthy people and for those with compromised immune systems, such as the elderly, Thom adds.

Russell Greenfield, MD, a leading practitioner of integrative medicine and medical director of Carolinas Integrative Health, advocates treating flu with black elderberry, he says in a news release. "It can be given to children and adults, and with no known side effects or negative interactions," he says.

"But don't expect grandma's elderberry jam" to ease flu symptoms like body aches, cough, and fever, he warns. "Sambucol is the only black elderberry preparation shown effective in clinical studies."

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