方法是病史，體檢，PCR和dot-blot hybridization methods。 基本上要有分子生物學和流行病學的基礎知識的。 這篇文章有900多個citation呢。
以下這篇文章認為處女和非處女HPV檢出率沒有顯著區別。用的也是PCR。 這是在台灣做的。
Possible non-sexual transmission of genital human papillomavirus infections in young women.
Pao CC , Tsai PL , Chang YL , Hsieh TT , Jin JY
Eur J Clin Microbiol Infect Dis.1993 Mar ; 12(3):221-2.
Human papillomaviruses were detected by an in vitro enzymatic DNA amplification method in cells obtained from vulvar swabs of 9 of 61 (14.8%) young women without prior experience of sexual intercourse and in 7 of 57 (12.3%) young women with prior experience. The prevalence of human papillomavirus DNA in these two groups of women was not significantly different (x2 = 0.16, p > 0.5; 95% confidence interval -0.165 to 0.215). These results suggest that genital human papillomavirus is not sexually transmitted in all cases and that it may be acquired by modes other than sexual contact.
PMID: 8389707 [PubMed - indexed for MEDLINE]
以下這篇文章認為處女和非處女HPV檢出率沒有顯著區別。用的也是PCR。 這是在台灣做的。
Possible non-sexual transmission of genital human papillomavirus infections in young women.
Pao CC , Tsai PL , Chang YL , Hsieh TT , Jin JY
Eur J Clin Microbiol Infect Dis.1993 Mar ; 12(3):221-2.
Human papillomaviruses were detected by an in vitro enzymatic DNA amplification method in cells obtained from vulvar swabs of 9 of 61 (14.8%) young women without prior experience of sexual intercourse and in 7 of 57 (12.3%) young women with prior experience. The prevalence of human papillomavirus DNA in these two groups of women was not significantly different (x2 = 0.16, p > 0.5; 95% confidence interval -0.165 to 0.215). These results suggest that genital human papillomavirus is not sexually transmitted in all cases and that it may be acquired by modes other than sexual contact.
PMID: 8389707 [PubMed - indexed for MEDLINE]
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