到pubmed去找一下，能找到案例報道。特別是兒童，有引起死亡的病例。下麵舉兩個比較近期的文獻。
個人不理解為什麽要吃有毒的東西來“養生”。如果一定要吃，建議放在小孩拿不到的地方。
個人不理解為什麽要吃有毒的東西來“養生”。如果一定要吃，建議放在小孩拿不到的地方。
Cyanide poisoning caused by ingestion of apricot seeds
Annals of Tropical Paediatrics， Volume 30 Issue 1 (01 March 2010), pp. 39-43
B. N. Akyildiz; S. Kurto?lu; M. Kondolot; A. Tunç
Aim: To report diagnostic, clinical and therapeutic aspects of cyanide intoxication resulting from ingestion of cyanogenic glucoside-containing apricot seeds.
Methods: Thirteen patients admitted to the Pediatric Intensive Care Unit (PICU) of Erciyes University between 2005 and 2009 with cyanide intoxication associated with ingestion of apricot seeds were reviewed retrospectively.
Results: Of the 13 patients, four were male. The mean time of onset of symptoms was 60 minutes (range 20 minutes to 3 hours). On admission, all patients underwent gastric lavage and received activated charcoal. In addition to signs of mild poisoning related to cyanide intoxication, there was severe intoxication requiring mechanical ventilation (in four cases), hypotension (in two), coma (in two) and convulsions (in one). Metabolic acidosis (lactic acidosis) was detected in nine patients and these were treated with sodium bicarbonate. Hyperglycaemia occurred in nine patients and blood glucose levels normalised spontaneously in six but three required insulin therapy for 3–6 hours. Six patients received antidote treatment: high-dose hydroxocobalamin in four and two were treated with a cyanide antidote kit in addition to high-dose hydroxocobalamin. One patient required anticonvulsive therapy. All patients recovered and were discharged from the PICU within a mean (SD, range) 3.1 (1.7, 2–6) days.
Conclusion: Cyanide poisoning associated with ingestion of apricot seeds is an important poison in children, many of whom require intensive care.
Acute Cyanide Toxicity Caused by Apricot Kernel Ingestion
Jeffrey R Suchard, MD, Kevin L Wallace, MD, Richard D Gerkin, MD
Abstract
A 41-year-old woman ingested apricot kernels purchased at a health food store and became weak and dyspneic within 20 minutes. The patient was comatose and hypothermic on presentation but responded promptly to antidotal therapy for cyanide poisoning. She was later treated with a continuous thiosulfate infusion for persistent metabolic acidosis. This is the first reported case of cyanide toxicity from apricot kernel ingestion in the United States since 1979. [Suchard JR, Wallace KL, Gerkin RD: Acute cyanide toxicity caused by apricot kernel ingestion. Ann Emerg Med December 1998;32:742-744.
From the Department of Medical Toxicology, Good Samaritan Regional Medical Center, Phoenix, AZ.
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