There are two subclusters of A which are distinguished by the synonymous
mutation T29095C. In the T-allele subcluster, four Chinese individuals (from
the southern coastal Chinese province of Guangdong) carry the ancestral
genome, while three Japanese and two American patients differ from it by a
number of mutations. These American patients are reported to have had a
history of residence in the presumed source of the outbreak in Wuhan. The C-
allele subcluster sports relatively long mutational branches and includes
five individuals from Wuhan, two of which are represented in the ancestral
node, and eight other East Asians from China and adjacent countries. It is
noteworthy that nearly half (15/33) of the types in this subcluster, however
, are found outside East Asia, mainly in the United States and Australia.
注意這句話：“four Chinese individuals (from the southern coastal Chinese province of Guangdong) carry the ancestral genome, while three Japanese and two American patients differ from it by a number of mutations.”
也是奇怪，武漢上傳的樣本並不多，和患病人數相比。
wyhz9311 發表評論於
Sample of 160 cases is definitely too small to be statistically meaningful. Considering the current population of Covid-19 patients has reached over 1.6 million, I do not see any significance of this research.
These authors only analyzed the first 160 sequences. Situation in Australia can be similar to those of WA and CA in the US: The early cases came from China, and the late cases are from US, Iran, and Europe. Nextstrain.org has the most updated information.
Search on youtube: "The first documentary movie on the origin of CCP virus(Coronavirus)"
playnice 發表評論於
如果能得出這樣的結論，真是傻了。
cawan 發表評論於
If we go to nextstrain.org to look at the sources of the sequencing data, we can see the submissions from Wuhan are rare and very few were submitted after early February. Would it be possible that "they" only sequenced/submitted sequences related to the seafood market, or just group B to mislead the rest of the world? Even though the authors use RaGT13 as the reference, which is in the hands of a Wuhan research group, this paper does NOT say the virus is originated somewhere else.
Dailymail reported the publication of this paper and the recent discoveries by two American teams. Figure in the paper clearly shows that all three, A, B, and C started from Wuhan.
