"It's always uncomfortable to grow."
Many of the things that are required to build and maintain healthy self-esteem can be uncomfortable, but the truth is they are essential. The good news is, with practice, uneasiness subsides and they become part of who you are.
Saying "No", and asserting yourself, asking for what you want, expressing your true feelings, saying positive things about yourself, letting someone love and nurture you...these may all be things that are uncomfortable. But, only at first.
One sure way to conquer discomfort is to simply do what is uncomfortable. Step away from complacency and dare to grow and develop yourself today. Start by choosing something that you have been put off. Then, just do it!