https://www.nytimes.com/interactive/2020/health/novavax-covid-19-vaccine.html
How the Novavax Vaccine Works
The Maryland-based company Novavax has developed a protein-based coronavirus vaccine called NVX-CoV2373. In March the company announced an efficacy rate of 96 percent against the original coronavirus, 86 percent against the B.1.1.7 variant and 49 percent against the B.1.351 variant.
Coronavirus Proteins
The SARS-CoV-2 virus is studded with proteins that it uses to enter human cells. These so-called spike proteins make a tempting target for potential vaccines and treatments.
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https://www.nytimes.com/2021/06/14/health/covid-vaccine-novavax.html
Novavax Offers U.S. a Fourth Strong Covid-19 Vaccine
By Carl Zimmer
June 14, 2021
Novavax, a small American company buoyed by lavish support from the U.S. government, announced on Monday the results of a clinical trial of its Covid-19 vaccine in the United States and Mexico, finding that its two-shot inoculation provides potent protection against the coronavirus.
In the 29,960-person trial, the vaccine demonstrated an overall efficacy of 90.4 percent, on par with the vaccines made by Pfizer-BioNTech and Moderna, and higher than the one-shot vaccine from Johnson & Johnson. The Novavax vaccine showed an efficacy of 100 percent at preventing moderate or severe disease.
Despite these impressive results, the vaccine’s future in the United States is uncertain and it might be needed more in other countries. Novavax says it may not seek emergency authorization from the Food and Drug Administration until the end of September. And with a plentiful supply of three other authorized vaccines, it’s possible that the agency may tell Novavax to apply instead for a full license — a process that could require several extra months.
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https://www.theatlantic.com/health/archive/2021/06/novavax-now-best-covid-19-vaccine/619276/
The mRNA Vaccines Are Extraordinary, but Novavax Is Even Better
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