Can antibody tests determine if the COVID-19 vaccine was effective?
The Centers for Disease Control and Prevention (CDC) discourages antibody testing for assessing immunity after getting the vaccine.
A vaccinated person is very likely to get a negative result from a serology test, even if the vaccine was successful and protective. That’s because different serology tests detect antibodies to different parts of the virus.
https://www.mdanderson.org/cancerwise/what-do-negative-positive-antibody-test-results-mean-after-a-covid-19-vaccine.h00-159459267.html#:~:text=The%20Centers%20for%20Disease%20Control,vaccine%20was%20successful%20and%20protective.