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https://www.nejm.org/doi/10.1056/NEJMc2101667
We found that a single dose of mRNA vaccine elicited rapid immune responses in seropositive participants, with postvaccination antibody titers that were similar to or exceeded titers found in seronegative participants who received two vaccinations. Whether a single dose of mRNA vaccine provides effective protection in seropositive persons requires investigation.
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A single dose, however, was 74% effective against COVID-related hospitalization and 72% effective at preventing death.