news: A new coronavirus variant is seen spreading across Europe

本帖於 2020-10-29 18:21:45 時間, 由普通用戶 fuz 編輯

https://www.cnbc.com/2020/10/29/coronavirus-variant-seen-spreading-across-europe-research-says.html


KEY POINTS

A new variant of the coronavirus, identified as 20A.EU1 by researchers from Switzerland and Spain, was first observed in Spain in June.
It has been recorded in Spain at frequencies of above 40% since July, the study said.
Elsewhere, the new variant of the coronavirus has increased from “very low” values prior to July 15 to 40% to 70% in Switzerland, Ireland, and the U.K. in September.
It was also found to be prevalent in Norway, Latvia, the Netherlands, and France.

 

 

The paper to be reviewed

https://www.medrxiv.org/content/10.1101/2020.10.25.20219063v1#disqus_thread

Abstract

A variant of SARS-CoV-2 emerged in early summer 2020, presumably in Spain, and has since spread to multiple European countries. The variant was first observed in Spain in June and has been at frequencies above 40% since July. Outside of Spain, the frequency of this variant has increased from very low values prior to 15th July to 40-70% in Switzerland, Ireland, and the United Kingdom in September. It is also prevalent in Norway, Latvia, the Netherlands, and France. Little can be said about other European countries because few recent sequences are available. Sequences in this cluster (20A.EU1) differ from ancestral sequences at 6 or more positions, including the mutation A222V in the spike protein and A220V in the nucleoprotein. We show that this variant was exported from Spain to other European countries multiple times and that much of the diversity of this cluster in Spain is observed across Europe. It is currently unclear whether this variant is spreading because of a transmission advantage of the virus or whether high incidence in Spain followed by dissemination through tourists is sufficient to explain the rapid rise in multiple countries.

 

所有跟帖: 

新的變異株(20A.EU1, A222V)從夏季起在歐洲許多國家流蕩。不知道現在的疫苗是否對這個變異有效 -fuz- 給 fuz 發送悄悄話 fuz 的博客首頁 (0 bytes) () 10/29/2020 postreply 18:24:01

. -盤山- 給 盤山 發送悄悄話 (0 bytes) () 10/29/2020 postreply 19:50:10

人們一直關注新冠病毒S蛋白的變異,以前是D614G。這裏是A222V,還有S477N... -賭城看客- 給 賭城看客 發送悄悄話 賭城看客 的博客首頁 (0 bytes) () 10/29/2020 postreply 20:13:27

. -盤山- 給 盤山 發送悄悄話 (0 bytes) () 10/29/2020 postreply 20:22:25

分了;有臨床數據;意義麽? -fuz- 給 fuz 發送悄悄話 fuz 的博客首頁 (0 bytes) () 10/29/2020 postreply 20:35:08

可能要過些日子會有變異對傳播、對預防和治療影響的文章。 -賭城看客- 給 賭城看客 發送悄悄話 賭城看客 的博客首頁 (0 bytes) () 10/29/2020 postreply 20:39:26

. -盤山- 給 盤山 發送悄悄話 (0 bytes) () 10/30/2020 postreply 04:46:55

外行了。病毒的分離與提純是兩碼事。前者著重生物學特性;後者研究理、化特征 -fuz- 給 fuz 發送悄悄話 fuz 的博客首頁 (624 bytes) () 10/30/2020 postreply 04:50:47

. -盤山- 給 盤山 發送悄悄話 (12 bytes) () 10/30/2020 postreply 05:37:01

嗯,放之四海而皆準 -fuz- 給 fuz 發送悄悄話 fuz 的博客首頁 (0 bytes) () 10/30/2020 postreply 07:37:17

有文章討論過,這個變種也許是二次感染的罪魁 -fuz- 給 fuz 發送悄悄話 fuz 的博客首頁 (485 bytes) () 10/30/2020 postreply 05:07:30

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