這種技術七十年前就有人研究,六十年前開始臨床試驗。二十年前美國公司開始生產商用機型。搞不懂王先生咋成了發明人

來源: fuz 2018-03-03 06:28:18 [] [博客] [舊帖] [給我悄悄話] 本文已被閱讀: 次 (11771 bytes)

The first investigations of HIFU for non-invasive ablation were reported by Lynn et al. in the early 1940s. Extensive important early work was performed in the 1950s and 1960s by William Fry and Francis Fry at the University of Illinois and Carl Townsend, Howard White and George Gardner at the Interscience Research Institute of Champaign, Ill., culminating in clinical treatments of neurological disorders. In particular High Intensity ultrasound and ultrasound visualization was accomplished stereotaxically with a Cincinnati precision milling machine to perform accurate ablation of brain tumors. Until recently, clinical trials of HIFU for ablation were few (although significant work in hyperthermia was performed with ultrasonic heating), perhaps due to the complexity of the treatments and the difficulty of targeting the beam noninvasively. With recent advances in medical imaging and ultrasound technology, interest in HIFU ablation of tumors has increased.

The first commercial HIFU machine, called the Sonablate 200, was developed by the American company Focus Surgery, Inc. (Milipitas, CA) and launched in Europe in 1994 after receiving CE approval, bringing a first medical validation of the technology for benign prostatic hyperplasia (BPH). Comprehensive studies by practitioners at more than one site using the device demonstrated clinical efficacy for the destruction of prostatic tissue without loss of blood or long term side effects. Later studies on localized prostate cancer by Murat and colleagues at the Edouard Herriot Hospital in Lyon in 2006 showed that after treatment with the Ablatherm (EDAP TMS, Lyon, France), progression-free survival rates are very high for low- and intermediate- risk patients with recurrent prostate cancer (70% and 50% respectively)[40] HIFU treatment of prostate cancer is currently[when?] an approved therapy in Europe[clarification needed], Canada, South Korea, Australia, and elsewhere.[citation needed] As of 2012, clinical trials for the Sonablate 500 in the United States are ongoing for prostate cancer patients and those who have experienced radiation failure.[41]

Use of magnetic resonance-guided focused ultrasound was first cited and patented in 1992.[42][43] The technology was later transferred to InsighTec in Haifa Israel in 1998. The InsighTec ExAblate 2000 was the first MRgFUS system to obtain FDA market approval[7] in the United States.

 

From https://en.m.wikipedia.org/wiki/High-intensity_focused_ultrasound

 

所有跟帖: 

不管誰研究出來的,能最好最快的造福人類,就是高明。。。。 -桃花好運- 給 桃花好運 發送悄悄話 (0 bytes) () 03/03/2018 postreply 06:45:16

問題在於,在這麽長時間裏,全世界這麽多聰明人,為啥沒有廣泛應用?隻把機會留給王先生用來造福中國人? -fuz- 給 fuz 發送悄悄話 fuz 的博客首頁 (0 bytes) () 03/03/2018 postreply 07:00:23

這隻能說明中國人更加聰明 -TBz- 給 TBz 發送悄悄話 TBz 的博客首頁 (101 bytes) () 03/03/2018 postreply 07:53:00

他的高明之處是不說他是照著別人學的。 -霧裏看花123- 給 霧裏看花123 發送悄悄話 霧裏看花123 的博客首頁 (0 bytes) () 03/03/2018 postreply 07:02:49

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