你這個擔憂很有道理啊! 即使是pd1抑製劑藥物，這種自身免疫反應副作用也不罕見。

這篇報道裏的例子就是聯用PD－1抑製劑和ctla 4抗體，免疫係統攻擊癌細胞很有效，但也攻擊胰髒，引起急性I型糖尿病。癌細胞控製住了，胰髒犧牲了。

... the autoimmune reactions were seen not only as an acceptable cost of these drugs but as evidence they were working.

“It’s the nature of the beast,” said Martin Bachmann, a professor and immunologist at the Jenner Institute, which is affiliated with Oxford University. “I’m not sure you can get rid of the side effects — it’s really what you want."

讀來令人動容。Oncologists are becoming immunologists.