Tumor markers used in ovarian cancer include:
CA-125
- Used to help in diagnosis, assessment of response to treatment, and monitoring for recurrence.
Alpha-fetoprotein (AFP)
- Used in ovarian germ cell tumors.
- Used to assess stage, prognosis, and response to treatment.
Beta-hCG (Beta Human Chorionic Gonadotropin)
- Used in ovarian germ cell tumors.
- Used to assess stage, prognosis, and response to treatment.
HE4
- HE4 can be used to help diagnose ovarian cancer in a woman with symptoms and may be more sensitive than CA125.
- It can also be used to assess response to treatment and monitor for recurrence.
Inhibin A & B
- A hormone that is normally produced by ovarian tissue, but may be elevated in certain types of ovarian cancer (mucinous epithelial carcinoma, granulosa cell tumors).
- Can be used to assess response to treatment and monitor for recurrence.
CEA (Carcinoembryonic antigen)
- Can be elevated in ovarian tumors and may be used to evaluate response to treatment.
