“After inflammatory activation, monocytes recruited to the intima express scavenger receptors that permit the uptake of modified LDL particles, such as oxidized LDL (oxLDL). Cholesterol loading leads to the formation of foam cells, and ultimately leads to the mature lipid-laden macrophages of the plaque's core.
In addition to modified LDL, triglyceride-rich lipoproteins such as very-low-density lipoprotein (VLDL) — particularly those particles that bear apolipoprotein C-III (Apo-CIII) or apolipoprotein B (Apo-B) — can instigate vascular inflammation through Toll-like receptor 2 (TLR2) signalling. ”
說的都是脂蛋白顆粒，lipoproteins的角色
