我看到的最新的一篇分析是說HDL-c和apoA-1越高的女性,患癌風險越低。

來源: 虎嗅薔薇 2016-10-19 14:43:18 [] [舊帖] [給我悄悄話] 本文已被閱讀: 次 (1379 bytes)
回答: 膽固醇太低易得癌症,這個說法對嗎?Gbdjw2016-10-19 10:53:36

Lipid biomarkers and long-term risk of cancer in the Women's Health Study

Total cancer risk was significantly lower in the highest quartile of apo A-I (adjusted HR: 0.79; 95% CI: 0.70, 0.90; P-trend = 0.0008) and HDL cholesterol (HR: 0.85; 95% CI: 0.75, 0.97; P-trend = 0.01). For site-specific cancers, significant associations included colorectal cancer risk with HDL cholesterol (HR: 0.63; 95% CI; 0.41, 0.98; P-trend = 0.03), triglycerides (HR: 1.86; 95% CI: 1.17, 2.97; P-trend = 0.02), and apo B-100 (HR: 1.60; 95% CI: 1.03, 2.49; P-trend = 0.006) and lung cancer risk with HDL cholesterol (HR: 0.59; 95% CI: 0.38, 0.93; P-trend = 0.01). LDL cholesterol was not significantly associated with risk of total cancer or any site-specific cancers. In time-dependent models that were adjusted for the use of a lipid-lowering medication after baseline, these associations remained.

甘油三酯高+apo B-100高(but not LDL-c)+HDL-c低,腸癌風險高。

 

 

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