這個樣子,可能目前不適合任何抗腫瘤治療。

來源: Diana-Sun 2016-05-13 17:56:31 [] [博客] [舊帖] [給我悄悄話] 本文已被閱讀: 次 (16508 bytes)

病人目前的一般情況按ECOG打分為3-4分。具體見下表。

抗腫瘤治療一般在患者ECOG 0-1 時進行。有時可以放寬到2。

可以用中藥支持治療,中西醫結合會更好。有貧血的要輸血,有粒細胞減少/缺乏的要用集落刺激因子,有水、電解質、酸堿失衡的要糾正,有抑鬱的要抗抑鬱治療幫助恢複體力,有感染的要抗感染治療等等。

等一般情況好轉了,再考慮抗腫瘤治療。這裏是Drugs Approved for Non-Hodgkin Lymphoma。 應先考慮使用這些藥物/方案,畢竟是臨床試驗證明有效的。pembrolizumab在血液腫瘤的療效還不確定,在實體瘤也不是每種類型效果都好的。

Karnofsky Status Karnofsky Grade ECOG Grade ECOG Status
Normal, no complaints 100 0 Fully active, able to carry on all pre-disease performance without restriction
Able to carry on normal activities. Minor signs or symptoms of disease 90 1 Restricted in physically strenuous activity but ambulatory and able to carry out work of a light or sedentary nature, e.g., light house work, office work
Normal activity with effort 80 1 Restricted in physically strenuous activity but ambulatory and able to carry out work of a light or sedentary nature, e.g., light house work, office work
Care for self. Unable to carry on normal activity or to do active work 70 2 Ambulatory and capable of all selfcare but unable to carry out any work activities. Up and about more than 50% of waking hours
Requires occasional assistance, but able to care for most of his needs 60 2 Ambulatory and capable of all selfcare but unable to carry out any work activities. Up and about more than 50% of waking hours
Requires considerable assistance and frequent medical care 50 3 Capable of only limited selfcare, confined to bed or chair more than 50% of waking hours
Disabled. Requires special care and assistance 40 3 Capable of only limited selfcare, confined to bed or chair more than 50% of waking hours
Severly disabled. Hospitalisation indicated though death nonimminent 30 4 Completely disabled. Cannot carry on any selfcare. Totally confined to bed or chair
Very sick. Hospitalisation necessary. Active supportive treatment necessary 20 4 Completely disabled. Cannot carry on any selfcare. Totally confined to bed or chair
Moribund 10 4 Completely disabled. Cannot carry on any selfcare. Totally confined to bed or chair
Dead 0 5 Dead

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非常感謝您的回複和信息,會和家人一起討論。謝謝! -Ghost99- 給 Ghost99 發送悄悄話 Ghost99 的博客首頁 (0 bytes) () 05/14/2016 postreply 06:22:46

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