據美國國家癌症研究所的最新估計，基於幾十年的研究，高達40％的那些遺傳到有害的BRCA1基因變異者到70歲時會發展為卵巢癌。而相比之下，普通女性在某階段患卵巢癌的機率大約1.4％。
According to the National Cancer Institute’s most recent estimates, based on decades of research, up to 40 percent of women who inherit a harmful BRCA1 mutation will develop ovarian cancer by age 70. That contrasts with the nearly 1.4 percent of women in the general population who will develop ovarian cancer sometime during their lives.
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Ask your doctor for genetic counseling. Genetic counselors are trained to help you determine which screenings may benefit you and protect your future health — and that includes screenings for BRCA1 and BRCA2. They also are trained to help you deal with what comes after a positive screening. They can help prepare you for critical conversations with surgeons about options such as prophylactic mastectomy, for example, and they’ll walk you through what to expect in terms of increased monitoring for cancer risk.
In the future, BRCA testing may become like a mammogram or colonoscopy — a routine part of care once you reach a certain age. But in the meantime, there are certainly steps we can take to protect more women from cancer.
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原文鏈接: http://health.clevelandclinic.org/2015/03/should-all-women-be-screened-for-brca1-and-brca2/
