[Cancer Letters] Acetic acid, a potent agent of tumor progressi

 

Cancer Letters

Volume 42, Issues 1–2, September–October 1988, Pages 87–90

Research letter

 

Acetic acid, a potent agent of tumor progression in the multistage mouse skin model for chemical carcinogenesis

• J.B. Rotstein, 
• T.J. Slaga

 

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doi:10.1016/0304-3835(88)90243-1

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Abstract

Acetic acid, a very weak tumor promoter in the multistage mouse skin model for chemical carcinogenesis, was found to be very effective at enhancing cancer development, when applied during the progression phase of the model. Papilloma-bearing mice when repeatedly treated with acetic acid had a greater carcinoma incidence and a greater conversion of papillomas to carcinomas than vehicle treated mice. Selective cytotoxicity is discussed as a possible mechanism.

 

Keywords

• chemical carcinogenesis; 
• mouse skin; 
• tumor progression; 
• acetic acid

 

Correspondence to: J.B. Rotstein.

Copyright © 1988 Published by Elsevier Ireland Ltd.

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• 你以為沒有嗎？早就有了。 -dudaan- ♂ (0 bytes) () 11/26/2014 postreply 20:36:45

• 人家是聞不是喝，喝太酸了吧胃受不了 -月光溶溶- ♀ (0 bytes) () 11/26/2014 postreply 20:11:27

• 醋酸有揮發性， 都聞到肺裏了。 -26484915- ♂ (0 bytes) () 11/26/2014 postreply 20:13:10

• 醋這個東西除了胃不好要注意外。沒聽說有什麽壞處。 -愛吃甜食- ♀ (0 bytes) () 11/26/2014 postreply 20:18:00

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• 用醋酸篩查宮頸癌是這樣操作的： -26484915- ♂ (273 bytes) () 11/26/2014 postreply 20:10:52