Remains of fossil humans indicate decrease in health status after the Neolithic. In most respects, the changes in diet from hunter-gatherer times to agricultural times have been almost all detrimental, although there is some evidence we'll discuss later indicating that at least some genetic adaptation to the Neolithic has begun taking place in the approximately 10,000 years since it began. With the much heavier reliance on starchy foods that became the staples of the diet, tooth decay, malnutrition, and rates of infectious disease increased dramatically over Paleolithic times, further exacerbated by crowding leading to even higher rates of communicable infections.
Skeletal remains show that height decreased by four inches* from the Late Paleolithic to the early Neolithic, brought about by poorer nutrition, and perhaps also by increased infectious disease causing growth stress, and possibly by some inbreeding in communities that were isolated. Signs of osteoporosis and anemia, which was almost non-existent in pre-Neolithic times, have been frequently noted in skeletal pathologies observed in the Neolithic peoples of the Middle East. It is known that certain kinds of osteoporosis which have been found in these skeletal remains are caused by anemia, and although the causes have not yet been determined exactly, the primary suspect is reduced levels of iron thought to have been caused by the stress of infectious disease rather than dietary deficiency, although the latter remains a possibility.[68]