首先，這隻是初步結果，隻是板藍根抗病毒感染的一個可能機製。第二，你自己也說了，in vitro結果不能完全translate成

第三，顯效劑量要和毒性和可耐受劑量比較。

謝謝你文中的信息，你很認真。但是我不能認同你的結論。

附：

板藍根的研究mskcc網站有些總結。現在學術界似乎還未下結論。

http://www.mskcc.org/cancer-care/herb/isatis-root

Isatis root exerts immunostimulatory effects by enhancing reticuloendothelial system function (11). Sinigrin and indigo have been identified as the compounds responsible for potential SARS inhibition (4). Clemastanin B, a major lignan compound in isatis, targets viral endocytosis, uncoating, and nuclear export of viral ribonucleoproteins (5). A crude extract of isatis root prevented influenza virus attachment to cells and therefore viral replication, but was inactive against respiratory syncytial virus, adenovirus, parainfluenza virus and enterovirus (19). Another component of isatis root demonstrates dose-dependent anti-endotoxic effects on lipopolysaccharide-induced expression of membrane-organizing extension spike protein, a main endotoxin receptor (10). Alkaloids isolated from isatis can inhibit leukocyte function and reduce inflammatory response (20). One animal study found that indigo root extract reduced tissue injury, enhanced hematopoietic system recovery, modulated serum inflammatory cytokines, and improved severe enteropathy in whole body irradiated mice (13).

An in vitro study also found that an ethanol extract of isatis root had a dose-dependent cytotoxic effect against human leukemia HL-60 cells (9). Indirubin, an active component of isatis, inhibits cyclin-dependent kinases (CDKs) and prevents proliferation by arresting cells in the G2/M phase (3).

所有跟帖： 

• 謝謝討論。鍾文的重點是功效不是機理。 -26484915- ♂ (92 bytes) () 08/21/2014 postreply 18:00:14