請問去年醫生給打的那一針是booster shot嗎?孩子是何時做的滴度檢查?是完成乙肝三針疫苗的若幹年後還是就在第三針乙肝疫苗後的一,兩個月後測的滴度.如果是後者(馬上在第三針乙肝疫苗後的一,兩個月後測的滴度<10 mIU/mL,是要考慮重打三針的.但若是過了若幹年後再測,抗體滴度<10 mIU/mL是很正常的,CDC目前不推薦注射加強針.認為第三針乙肝疫苗後的一,兩個月後測的post vaccination titer testing>10 mIU/mL,那是有免疫力的.一些研究文章也支持: 雖然抗體滴度下降,但一個人的免疫功能正常的話,健康者是可以靠自己的免疫力(免疫記憶)抵抗乙肝病毒的.隻有那些免疫功能低下者和一些高風險人群(比如一些特定的醫務人員(抽血員),共用針頭濫用注射藥物者或無保護的性工作者等...)才需要考慮重打三針係列.所以何時做孩子的post vaccination titer testing很關鍵.
抱歉,我不是專家,也不懂.必要時約看和谘詢GI或Hepatologist專科醫生.下麵的兩個鏈接我覺得不錯,和你一起學習:
1. What Should I Know About a Hepatitis B Titer?
The Centers for Disease Control and Prevention (CDC) recommends HBV vaccination be given by intramuscular injection at 0, 1, and 6 months. Postvaccination testing is not a routine practice except for infants born to mothers with HBV, immune compromised persons, healthcare workers, and sex partners of persons with chronic HBV. For the adult, a titer should be drawn 1 to 2 months after completing the vaccination series. For infants born from HBV-positive mothers, the testing should be done 3 to 9 months after receiving the vaccination series.
The CDC does not currently recommend revaccination in persons with intact immune systems. However, there is a 15-year span after vaccination where antibodies decline but protection is still afforded (the so-called "immune memory"). If a person who took the series never had a test to check for immunity, it may be wise to assess for adequate hepatitis B surface antibody (HBsAb) levels, indicating protection against hepatitis B antigen (HBsAg). (HBsAg is a serologic marker that indicates that the person is actively infectious.) If the patient tests HBsAb negative, indicating a lack of protection from HBV infection, a second series is recommended.[2](重新打三針)
......第二個鏈接共兩頁,有更詳細的Q&A:
2. Hepatitis B Vaccination FAQ - Stanford University
