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In 1992, William P. Castelli of Framingham, the former director of a
study that’s been running for more than 50 years, the largest study into
the relationship between saturated fat consumption, blood cholesterol
levels and coronary heart disease, wrote in an editorial in the Archives
of Internal Medicine the following words: “In Framingham,
Massachusetts, the more saturated fat one ate, the more cholesterol
one ate, the more calories one ate, the lower the person’s serum
cholesterol…the opposite of what the equations provided by Hegsted
et al and Keys et al would predict.”