正好學到這篇文章,公論是副作用挺大的,



Atypical Subtrochanteric and Diaphyseal Femoral
Fractures: Report of a Task Force of the American
Society for Bone and Mineral Research

However, recent observations suggest that the risk rises with increasing duration of exposure, and there is concern that

lack of awareness and underreporting may mask the true incidence of the problem. Given the relative rarity of atypical femoral fractures,

the task force recommends that specific diagnostic and procedural codes be created and that an international registry be established to

facilitate studies of the clinical and genetic risk factors and optimal surgical and medical management of these fractures. Physicians and

patients should be made aware of the possibility of atypical femoral fractures and of the potential for bilaterality through a change in

labeling of BPs. Research directions should include development of animal models, increased surveillance, and additional epidemiologic

and clinical data to establish the true incidence of and risk factors for this condition and to inform orthopedic and medical management.

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