大家對Angelina Jolie的乳腺癌預防手術怎麽看？

有必要麽？

http://www.cnn.com/2013/05/14/showbiz/angelina-jolie-double-mastectomy/index.html?hpt=hp_t1

(CNN) -- Actress Angelina Jolie announced in a New York Times op-ed article on Tuesday that she underwent a preventive double mastectomy after learning she carries a mutation of the BRCA1 gene, which sharply increases her risk of developing breast cancer and ovarian cancer.

"My doctors estimated that I had an 87 percent risk of breast cancer and a 50 percent risk of ovarian cancer, although the risk is different in the case of each woman," Jolie wrote. "Once I knew that this was my reality, I decided to be proactive and to minimize the risk as much I could. I made a decision to have a preventive double mastectomy."

Jolie's mother, actress and producer Marcheline Bertrand, died of ovarian cancer in 2007 at the age of 56. Jolie is 37 years old.

In the Times op-ed, titled "My Medical Choice," Jolie said she finished three months of medical procedures at the Pink Lotus Breast Center in California on April 27 that included the mastectomies and reconstruction.

Opinion: Jolie's choice carries risks with benefits

A mastectomy is an operation that removes all or part of the breast.

Jolie: 'I've decided to be proactive'

CNN anchor: I have breast cancer

Explaining Jolie's cancer gene

CNN archives: Jolie on her mom's cancer

Photos: Life of Angelina Jolie

She wrote that her experience involved a three-step process. On February 2, the actress had a procedure that increases the chance that the nipple can be saved. Two weeks later, she had major surgery where the breast tissue was removed and temporary fillers were put in place. Nine weeks later she described undergoing "reconstruction of the breasts with an implant."

"There have been many advances in this procedure in the last few years," she said, "and the results can be beautiful."

Why double mastectomies are up

"I wanted to write this to tell other women that the decision to have a mastectomy was not easy. But it is one I am very happy that I made," Jolie wrote. "My chances of developing breast cancer have dropped from 87 percent to under 5 percent."

BRCA stands for breast cancer susceptibility genes -- a class of genes known as tumor suppressors, according to the National Cancer Institute.

Hollywood applauds Jolie for going public with surgery

Mutations of the BRCA1 and BRCA2 genes have been linked to hereditary breast and ovarian cancer. A blood test can determine if a woman is "highly susceptible" to the cancers.

Fellow actress Christina Applegate had a similar procedure in 2008. She also had a mutation of the BRCA1 gene.

所有跟帖： 

• 我比較同意一位讀者的觀點 -閑情- ♀ (4662 bytes) () 05/14/2013 postreply 09:18:39

• 可以用肚子上的脂肪隆乳。 不是非得用矽膠。 -如塵- ♀ (0 bytes) () 05/14/2013 postreply 12:20:01

• Jolie 肚子上好像沒啥脂肪：） -viewfinder- ♀ (0 bytes) () 05/14/2013 postreply 13:18:56

• 多采用背闊肌瓣帶蒂轉移術 -禦用文人- ♀ (0 bytes) () 05/14/2013 postreply 17:41:02

• 個人認為不推薦！把乳腺全部切除沒留一個乳腺細胞是很難的！ -回家路- ♂ (0 bytes) () 05/14/2013 postreply 09:35:24

• 都是被假科學忽悠的。不過幫助了美國的GDP.就是因為這些花費,美國的GDP的1/3是醫療行業提供的。 -薛成- ♂ (0 bytes) () 05/14/2013 postreply 09:38:14

• 你太偏激了。這個不是假科學是真科學。 -Bluebell- ♀ (0 bytes) () 05/14/2013 postreply 11:05:48

• 那麽，生活質量就不用考慮了？ -薛成- ♂ (0 bytes) () 05/14/2013 postreply 18:44:28

• 她的醫生應該和她討論過這個問題 -TBz- ♂ (82 bytes) () 05/15/2013 postreply 09:24:15

• 科學過頭了！真是基因缺陷要致癌的話，乳腺切了不能長了，還得在其它地方長，不是更不好治？ -福娃2009- ♀ (0 bytes) () 05/15/2013 postreply 08:38:15

• 她的醫生認為她有90%幾率得乳腺癌，切除了就幾乎為零幾率。可以理解她的選擇。 -viewfinder- ♀ (101 bytes) () 05/14/2013 postreply 10:26:40

• 今天中午和我先生一起吃飯我們談起她 -Bluebell- ♀ (227 bytes) () 05/14/2013 postreply 11:04:53

• 這個真不是個容易的選擇，就是在醫學界也有爭議。 -viewfinder- ♀ (282 bytes) () 05/14/2013 postreply 11:18:13

• 如果是你得了 -蒙城一郎中- ♂ (226 bytes) () 05/14/2013 postreply 12:12:41

• 郎中啊！你終於出現啦！：）））） -Bluebell- ♀ (249 bytes) () 05/14/2013 postreply 12:26:47

• 如果你老公 -蒙城一郎中- ♂ (314 bytes) () 05/14/2013 postreply 12:46:25

• 不理解你的邏輯. 老公沒有注意到老婆的身體健康, 也不該把JJ切掉啊. -永遠是中國人- ♂ (65 bytes) () 05/14/2013 postreply 12:53:17

• 邏輯. 老公把JJ切掉啊，也能預防JJ癌 -蒙城一郎中- ♂ (0 bytes) () 05/14/2013 postreply 12:54:11

• 搬馬紮磕瓜子等著看郎中挨砸 ：）） -Bluebell- ♀ (0 bytes) () 05/14/2013 postreply 12:59:27

• 憑什麽挨砸 ：）） -蒙城一郎中- ♂ (52 bytes) () 05/14/2013 postreply 13:01:28

• 為什麽不砸你 -Bluebell- ♀ (121 bytes) () 05/14/2013 postreply 13:03:35

• 砸我才沒天理咧 -蒙城一郎中- ♂ (222 bytes) () 05/14/2013 postreply 13:06:22

• 人法地 地法天 天法道 道法自然 -Bluebell- ♀ (173 bytes) () 05/14/2013 postreply 13:24:03

• 這就你的不科學了哈～ -蒙城一郎中- ♂ (428 bytes) () 05/14/2013 postreply 13:38:17

• 郎中今天這麽文青哈～ -Bluebell- ♀ (186 bytes) () 05/14/2013 postreply 13:59:07

• 抱下抱下，咱倆不打架 ：））））） -Bluebell- ♀ (190 bytes) () 05/14/2013 postreply 12:57:15

• 我阿姨婚姻幸福得很，乳癌去年走了。 -如塵- ♀ (0 bytes) () 05/14/2013 postreply 12:41:53

• 回複：大家對Angelina Jolie的乳腺癌預防手術怎麽看？ -周遊列國逍遙人生- ♂ (36 bytes) () 05/14/2013 postreply 10:28:57

• 是的，日本女人移民到美國後，乳腺癌發病率增加10倍以上！飲食環境因素也是很重要的！ -回家路- ♂ (0 bytes) () 05/14/2013 postreply 10:53:54

• BRCA1基因，科學研究證實是遺傳的。 -TBz- ♂ (0 bytes) () 05/14/2013 postreply 13:00:53

• 得癌幾率87%,這個基因當然不是100%絕對生效的 -TBz- ♂ (0 bytes) () 05/14/2013 postreply 15:04:48

• 能做出這樣的決定需要勇氣，尤其是她媽和她外婆都早逝，她又有87%的發病幾率 -tiger00- ♀ (137 bytes) () 05/14/2013 postreply 11:49:10

• “雙側切了還肺癌腦癌的”，那還得預先切肺切腦？癌症因素不去除，切哪也沒用。 -ooopsss- ♂ (0 bytes) () 05/14/2013 postreply 12:00:00

• in her case, the probability is reduced from 87% to 5%. -如塵- ♀ (0 bytes) () 05/14/2013 postreply 12:23:27

• agree -Bluebell- ♀ (0 bytes) () 05/14/2013 postreply 12:29:09

• 美國人很相信概率數字。 但是有幾個人真正明白概率是什麽，怎麽解讀那個數字？ -lavendar99- ♀ (149 bytes) () 05/14/2013 postreply 12:32:20

• 是應該認真解讀這個數字。87%是life time患乳腺癌幾率， -viewfinder- ♀ (460 bytes) () 05/14/2013 postreply 13:09:18

• 這個，也需要這樣解讀，有乳腺，就有可能生乳癌，不分男女。沒有乳腺，何來乳癌？此概率為0。。。因此，推動另外1種人類之思。 -大江川- ♂ (0 bytes) () 05/14/2013 postreply 15:42:26

• 九成得癌的機會還不切除？為什麽拿性命賭？我覺得明智 -ECityBlues- ♀ (185 bytes) () 05/14/2013 postreply 12:47:19

• 拚命點頭，對對對 -Bluebell- ♀ (48 bytes) () 05/14/2013 postreply 13:00:49

• 而且， 孩子生完了， 那啥本來也木啥用 ， 對吧 ：） -如塵- ♀ (0 bytes) () 05/14/2013 postreply 13:06:13

• 但她的mammogram現在肯定正常！她也可能一輩子根本不會得癌。對個人來說，機率要麽0%, 要麽100%. -回家路- ♂ (0 bytes) () 05/14/2013 postreply 13:21:26

• 她有87%的可能100%得癌 -Bluebell- ♀ (0 bytes) () 05/14/2013 postreply 13:25:48

• 她一輩子不得癌的幾率１３％， 得癌的幾率８７％。 -如塵- ♀ (0 bytes) () 05/14/2013 postreply 13:36:09

• 是的，按著整體概率她真該切，但馬上切不切還有很大爭議！因為還有其他選擇！ -回家路- ♂ (0 bytes) () 05/14/2013 postreply 13:40:25

• 剛問了診所的一個年輕女孩，她是積極讚成的，她說，女士要做breast plant anyway! -回家路- ♂ (0 bytes) () 05/14/2013 postreply 13:46:02

• 那不是還要做chemo？ 我一個做過chemo的朋友說： -如塵- ♀ (36 bytes) () 05/15/2013 postreply 07:37:13

• 完全同意！其實文章沒說，即使切掉也要密切監測！還有機會在局部得的！ -回家路- ♂ (0 bytes) () 05/15/2013 postreply 08:46:57

• 這個是人家的選擇，怎麽看也沒用，反正不犯法。愛咋咋地。 -Déjàvu116- ♀ (0 bytes) () 05/14/2013 postreply 16:08:52

• 高危不代表準得病，隻是個統計數字罷了。 -Déjàvu116- ♀ (204 bytes) () 05/14/2013 postreply 16:13:01

• 把能切的都切了，神經該有問題了～～～～ -lavendar99- ♀ (0 bytes) () 05/14/2013 postreply 17:20:40

• 哈哈哈，含蓄點兒。。。 -Déjàvu116- ♀ (0 bytes) () 05/14/2013 postreply 17:21:44

• Talk to Genetic Counselors -tiaa-cref- ♂ (0 bytes) () 05/14/2013 postreply 16:09:30

• Talk to Genetic Counselors -tiaa-cref- ♂ (246 bytes) () 05/14/2013 postreply 16:10:32

• 不覺得是最好的選擇！！ -Déjàvu116- ♀ (0 bytes) () 05/14/2013 postreply 16:14:11

• 洗耳恭聽，您給說說最好的選擇是啥？ -Bluebell- ♀ (0 bytes) () 05/14/2013 postreply 18:05:09

• 弄個假的沒有刺激感覺，多活幾年又有什麽意思？-〉錢多撐的。 -faday- ♀ (0 bytes) () 05/14/2013 postreply 16:45:05

• 你肯定不是當媽的。。。。 -Bluebell- ♀ (62 bytes) () 05/14/2013 postreply 18:06:51

• 乳腺癌預防手術有一點aggressive,但可以理解. -Lilac2003- ♀ (0 bytes) () 05/15/2013 postreply 08:28:27

• 即使切掉後，也要close follow up. 隻是得的機會少了，但還會在局部得！並不是全放下心來！ -回家路- ♂ (0 bytes) () 05/15/2013 postreply 08:42:17