機器翻譯:
《胸腺素α1治療癌症:從基礎研究到臨床應用》https://www.sciencedirect.com/science/article/abs/pii/S0192056100000758?via%3Dihub
摘要
許多研究探索了免疫療法單獨或與常規療法聯合對實驗性癌症和人類癌症的影響。有證據表明,胸腺素 α1 (Tα1) 和低劑量幹擾素 (IFN) 或白細胞介素 (IL)-2 的聯合治療在恢複因腫瘤生長和/或細胞抑製藥物抑製的幾種免疫反應方麵非常有效。此外,與特異性化療相結合時,它們能夠增加化療的抗腫瘤作用,同時顯著降低治療的一般毒性。本期綜述了在實驗性癌症和人類癌症中使用這種聯合化學免疫治療方法的優勢。
Thymosin alpha 1 in the treatment of cancer: from basic research to clinical application,https://www.sciencedirect.com/science/article/abs/pii/S0192056100000758?via%3Dihub
Abstract
Many studies have explored the effects of immunotherapy, alone or in combination with conventional therapies, on both experimental and human cancers. Evidence has been provided that combined treatments with thymosin alpha 1 (T α 1) and low doses of interferon (IFN) or interleukin (IL)-2 are highly effective in restoring several immune responses depressed by tumor growth and/or cytostatic drugs. In addition, when combined with specific chemotherapy, they are able to increase the anti-tumor effect of chemotherapy while markedly reducing the general toxicity of the treatment. The advantages of using this combined chemo-immunotherapeutic approach in experimental and human cancers are reviewed in this issue.
Thymosin alpha 1 in the treatment of cancer: from basic research to clinical application
Abstract
Many studies have explored the effects of immunotherapy, alone or in combination with conventional therapies, on both experimental and human cancers. Evidence has been provided that combined treatments with thymosin alpha 1 (T α 1) and low doses of interferon (IFN) or interleukin (IL)-2 are highly effective in restoring several immune responses depressed by tumor growth and/or cytostatic drugs. In addition, when combined with specific chemotherapy, they are able to increase the anti-tumor effect of chemotherapy while markedly reducing the general toxicity of the treatment. The advantages of using this combined chemo-immunotherapeutic approach in experimental and human cancers are reviewed in this issue.