Nobel for TCM ? Not yet

如何將2017年生理學（生物鍾）諾貝爾獎的靈感推動中醫理論發展？
如何將2017年生理學（生物鍾）諾貝爾獎的靈感推動中醫理論發展？

已有 37 次閱讀 2017-10-3 09:13 |個人分類:Thought Leader|係統分類:論文交流    推薦到群組  

如何將2017年生理學（生物鍾）諾貝爾獎的靈感推動中醫理論發展？

你如何播種，將2017年諾貝爾生理學獎得主的靈感翻譯成中醫理論？

 

Some company (see Ref., below,  ScienCell Research Laboratories | 6076 Corte Del Cedro. Carlsbad, CA) reap the fruit of 2017 Nobel prize in Physiology/Medicine. Take a free ride - why not?

 

It's pure instinct for me to write this post (below), simply from my own experience. Any good TCM doctors provided me with their prescriptions granted me a sound sleep - I guess their TCM medicine improved my internal biological clock, for someone like me suffering from insomnia.

 

諾貝爾獎2017生理醫學生物鍾給中醫指明方向 http://blog.sciencenet.cn/blog-847277-1078861.html  

 

How can you sow the seed to translate the inspiration of 2017 Nobel prize in Physiology/Medicine to TCM (中醫)?

Here are some thoughts:

1) basal levels of those biological clock before TCM - pathological readout (molecular assays, see Ref.)

2) molecular changes upon TCM treatment (time course study up to TCM efficacy time point - six months or longer)

3) It's cliche to mold molecular bio-clock theory to TCM mechanism; however, it's a way to compliment TCM holistic management with such theory. Nothing to hurt TCM, but doing nothing hurts much worse.

 

(Robotic translation - not proof-reading as I jot down/drop off my thoughts here, hoping I'll come back to visit this topic. Rushing through many ideas daily is a problem now as I got too much to do, with too little time)

你如何播種，將2017年年諾貝爾生理學獎得主的靈感翻譯成中醫？
植物，動物和人類將其生物節奏與地球的革命相適應，這樣他們都可以保持同步。科學家知道這幾個世紀之前，他們明白了什麽使他們勾選。美國三位科學家Jeffrey C Hall，Michael Rosbash和Michael W Young一直致力於研究內部生物鍾的見解。他們確定了果蠅內的基因，負責控製日常節律，稱為周期基因。該基因的轉錄水平隨著我們星球的旋轉而振蕩。研究獲得了2017年諾貝爾生理學/醫學獎。內部時鍾是地球上生命的一個重要特征，將地球的旋轉連接到數百萬年演進的細胞織物中。

 

** Ref. **

Subject	Nobel Prize: the 24-hour Body Clock Study
From	Sciencell Research Laboratories
To
Date	Today 05:56

     

Primary Cells | qPCR Array Kits | Gene Database | Gene Expression Blog | Custom Order Plants, animals, and humans adapt their biological rhythm with

 

Web Version   Primary Cells | qPCR Array Kits | Gene Database | Gene Expression Blog | Custom Order GeneQuery™ Human Circadian Rhythm qPCR Array Kit Catalog #GK060 GeneQuery™ Human Circadian Rhythm qPCR Array Kit Catalog #GK060 Plants, animals, and humans adapt their biological rhythm with the Earth's revolutions, this way they can all stay synchronized. Scientists knew these centuries before they understood what made them tick. Three American scientists, Jeffrey C Hall, Michael Rosbash and Michael W Young, have been dedicated their research for insights into the internal biological clock. They identified a gene within fruit flies responsible for controlling the daily rhythm, known as period gene. The transcription level of this gene oscillates with the rotation of our planet. The research won them the 2017 Nobel Prize in Physiology/ Medicine. The internal clock is a key feature of life on Earth, one that wired the rotation of the planet into the fabric of our cells over millions of years of evolution. ScienCell's GeneQuery™ Human Circadian Rhythm qPCR Array Kit (GQH-CIR) profiles 88 key genes involved in regulating changes that occur on a roughly 24-hour cycle. Why use GeneQuery™ arrays? * Genes are selected based on extensive literature research by our Ph.D. scientist team * All known transcript variants of target gene are recognized * Primers are verified with over 10 types of normal human primary cells to assure universal specificity and biological relevance * Performance guaranteed with high efficiency and reproducibility; free of non-specific amplification * Customizable with no extra charge * Individual primers available Example applications: Basic research * Identify cell signaling aberrancies * Determine relevancy of biological pathways * Study gene expression manipulation * Examine mechanisms that may characterize phenotypes * Compare cell functionality and biology in various conditions * Confirm clustered RNA-Sequencing, microarrays and other preliminary data Translational research * Evaluate novel target genes or markers in discovery biology * Determine drug mechanism of action in drug screening * Evaluate new drug performance and enhance development Connect with ScienCell

 

轉載本文請聯係原作者獲取授權，同時請注明本文來自李勝文科學網博客。
鏈接地址：http://blog.sciencenet.cn/blog-847277-1079033.html