是牛頓啟發了數學家要解釋自然界必須用無限小。萊才努力從數學的角度發展出他的微積分。
In early calculus the use of infinitesimal quantities was thought unrigorous, and was fiercely criticized by a number of authors, most notably Michel Rolle and Bishop Berkeley. Berkeley famously described infinitesimals as the ghosts of departed quantities in his book The Analyst in 1734. Working out a rigorous foundation for calculus occupied mathematicians for much of the century following Newton and Leibniz, and is still to some extent an active area of research today.
For centuries, mathematicians and philosophers wrestled with paradoxes involving division by zero or sums of infinitely many numbers. These questions arise in the study of motion and area. The ancient Greek philosopher Zeno of Elea gave several famous examples of such paradoxes. Calculus provides tools, especially the limit and the infinite series, which resolve the paradoxes.