1, A new medication called Radicava (edaravone) was approved in May 2017 for the treatment of amyotrophic lateral sclerosis (ALS). It was approved in Japan before it was approved in the United States. This is a significant development because it is the first FDA approved drug for ALS in over 20 years.
2. A medication called Riluzol was approved in 1996. This medication is believed to work by decreasing the action of a chemical called glutamic acid, which is known to overstimulate the nervous system, potentially causing permanent damage to the nerves.
https://www.verywellhealth.com/radicava-treatment-option-for-als-4142146