Norovirus causes acute gastroenteritis in all age groups. Afebrile convulsion is an occasional neurologic complication in norovirus infection, but encephalitis is rare. We report the case of a previously healthy 15-month-old girl with norovirus encephalopathy who had a poor neurologic outcome. Norovirus (genogroup II) was detected in plasma and stool by real-time reverse transcription polymerase chain reaction, but the cerebrospinal fluid showed negative result for genome. Elevated concentrations of cerebrospinal fluid interleukin-6, interleukin-10, interferon-γ, and tumor necrosis factor-α were observed on the third day of illness. The encephalopathy in our patient may be related to hypercytokinemia rather than to direct viral invasion.
諾如病毒引起的腦病罕見,但是有報道
所有跟帖:
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中文:部分患兒可伴有低熱、呼吸道症狀,偶有驚厥、腦病、腦炎
-dudaan-
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01/30/2019 postreply
18:58:18
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謝謝你找到這方麵的病例報道
-妹吉大人-
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01/30/2019 postreply
19:16:18
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日本那個病例預後不好
-dudaan-
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01/30/2019 postreply
19:19:35
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事到如今也隻能做好最壞的心理準備,但隻要還有一絲康複的希望就要盡最大力氣去爭取。
-妹吉大人-
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01/30/2019 postreply
19:41:25