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Ginseng complex, while generally considered safe for short-term use, can cause side effects and interact with medications. Common side effects include digestive issues like nausea and diarrhea, headache, insomnia, and changes in blood pressure or heart rate. More serious, but less common, side effects can include allergic reactions, liver problems, and even severe skin reactions. It's crucial to be aware of potential interactions with other medications, especially blood thinners, diabetes medications, and certain mental health drugs.