Asthma induced by ice water ingestion in ethnic Chinese asthmatic children: a challenge.
Author information
- 1Department of Pediatrics, Taipei Municipal Chung Hsiao Hospital, Taiwan, R.O.C.
Abstract
The purpose of this study was to investigate the relationship between ice water ingestion and the induction of asthmatic symptoms and signs in ethnic Chinese asthmatic children. Sixty asthmatic children with a positive history of exacerbation of symptoms after drinking ice water were divided randomly into two groups: 34 children were instructed to drink 250 ml of 0-4 degrees C ice water within one minute, and 26 to drink 250 ml of 25 degrees C warm water. All of the asthmatic children were stable when studied. Twenty-three healthy children as controls were asked to drink 250 ml of 0-4 degrees C ice water. The three groups had forced expiratory volume in one second (FEV1) performed at baseline and at 5, 15, 30, 60, and 90 minutes after challenge. After the spirometric test at 90 minutes the patients of the two asthmatic groups received three puffs (0.6 mg) of hexoprenaline MDI and a further spirometric test was performed 5 min after the inhalation. Cough and wheeze were monitored throughout the course of the test. The mean FEV1 after challenge decreased significantly only in the ice-water asthmatic group (p = 0.004). Compared with the baseline data, the mean FEV1 at various periods after challenge was only significantly decreased at 60 min (p = 0.035). After hexoprenaline inhalation the FEV1 significantly increased in the two asthmatic groups (p < 0.001). A significant difference in FEV1 change was noted among the three groups (p = 0.015). Nine cases (26%) from the ice water asthmatic group, three (12%) from the warm-water asthmatic group, and none of the ice-water normal control group showed a decrease of FEV1 greater than 15% (p = 0.018). The greatest difference occurred between the two ice water groups. All six cases who developed symptoms after challenge, accompanied by a simultaneous decrease of FEV1 greater than 15%, belonged to the ice-water asthmatic group. Forty-seven percent of the ice-water asthmatic group and 4% each of the two other groups had cough and/or wheeze after challenge (p = 0.0002).
IN CONCLUSION:
Ice water ingestion may induce or exacerbate asthma in ethnic Chinese asthmatic children.
- PMID:
- 9260213
- [PubMed - indexed for MEDLINE]
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4 Hidden Ways Drinking Ice-Cold Water Is Bad For ... - Daily Health Post
dailyhealthpost.com/4-hidden-ways-drinking-ice-cold-water-is-bad-for-you/Sep 30, 2015 - Cold water can exacerbate asthma symptoms in children, according to a study by the Eurpean Society of Pediatric Allergy and Immunology
Acta Paediatr Taiwan. 2000 Jul-Aug;41(4):184-8.Effect of ice water ingestion on asthmatic children after exercise challenge.
Author information
- 1Department of Pediatrics, Taiwan Adventist Hospital, Taipei, Taiwan.
Abstract
Both exercise and ice water ingestion are known to be trigger factors for an asthma attack in ethnic Chinese asthmatic children. The purpose of this study was to investigate whether ice water ingestion further deteriorates pulmonary function of asthmatic children after exercise. Thirty Chinese asthmatic children underwent exercise challenge by ergocyclometer for 6 minutes and then were further challenged by immediate ingestion of ice water (200 ml, 0-4 degrees C), warm water (200 ml, 37 degrees C) or no ingestion on three different days in one week. Each patient completed the three different water ingestion tests after exercise challenge. The FEV1, FEF25-75%, and PEF tests were performed at baseline and again at 5, 15, 30, 60, 90 minutes after exercise plus water ingestion challenge. After the spirometric test at 90 minutes, 3 puffs (0.6 mg) of hexoprenaline from a metered dose inhaler were given and then a further spirometric test was performed 15 minutes later. The FEV1 and PEF were significantly decreased after exercise plus the 3 different water ingestion challenge except for the FEV1 in the patients who ingested nothing (p = 0.051) and PEF in the patients who ingested warm water (p = 0.163). FEF25-75% of the three tests was not significantly decreased. Exercise-induced asthma (EIA) developed in about two thirds of the 30 patients, regardless of whether ice water, warm water or nothing at all was ingested after exercise challenge. There was no statistically significant difference in spirometric data among the 3 different water tests at various time points. The mean percentage increase of FEV1, FEF25-75% and PEF after bronchodilator therapy were all the lowest in the ice water test, and the greatest in the warm water test. A statistically significant difference was found between ice water and warm water tests for FEV1 and PEF (p = 0.0293 and p = 0.0308 respectively). In conclusion, about two thirds of the asthmatic children in this series had EIA. Those who ingested warm water after exercise had a better bronchodilator response than those who ingested ice water.
- PMID:
- 11021003
- [PubMed - indexed for MEDLINE]
