啥叫I型糖尿病：https://dtc.ucsf.edu/zh-hans/糖尿病分型/1型糖尿病/了解1型糖尿病/什麽是1型糖尿病/
1型糖尿病的發生，是因為生產胰島素的細胞數量減少或功能不全, 這種細胞叫胰島B細胞。B細胞損傷導致體內胰島素分泌不足或消失。多數1型糖尿病患者有自身免疫基礎，患者自身的免疫係統錯誤地攻擊並破壞B細胞。因為胰島素對維持生命至關重要，所以不足的胰島素一定要補充。補充胰島素可以用注射器或胰島素泵來皮下注射。
除了胰島素替代療法，近年來幹細胞移植技術給了“一糖”患者新的希望。
https://pubmed.ncbi.nlm.nih.gov/30362170/
https://stemcellres.biomedcentral.com/articles/10.1186/s13287-020-01793-6
https://www.ucihealth.org/blog/2020/03/diabetes-clinical-trial
The phase 1/2 study will determine whether the islet cell replacement therapy, a device called PEC-Direct, is safe and can provide blood glucose control in a manner similar to an artificial pancreas.
https://www.cryo-cell.com/treatments-and-research/diabetes
Brazilian Study Treating Type I Diabetes
A clinical trial conducted in Brazil comprising 21 adult patients with type 1 diabetes shows that a stem cell infusion may remedy the disease, at least for a number of years. Published during 2017 in the journal Frontiers in Immunology, the results showed that most patients became insulin-free for three and a half years and one patient did not have to use insulin for eight years. “We now understand stem cell transplants can succeed in treating diabetes for some,” said Bart Roep, Ph.D., the Chan Soon-Shiong Shapiro Distinguished Chair in Diabetes, professor/founding chair of the Department of Diabetes Immunology and monitor of the clinical trial.
These positive outcomes were not the rule. For some patients, the stem cell transplant had little to no effect on their type 1 diabetes (T1D).
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Current Clinical Trials
A study out of Australia is recruiting children between the ages of 1 and 12 to see if a re-infusion of their own cord blood can help prevent type I diabetes in those who are at an enhanced risk.
The Institute of Metabolism and Endocrinology in China has a pair of studies looking at Treg cells from cord blood for diabetes.
A study on the Stem Cell Educator is currently in trial in China.
Another three different studies in China are using cord tissue stem cells for patients with diabetes.
A clinical trial in Vietnam is also looking at how cord tissue stem cells can treat the condition.
