這個是解釋為什麽打胰島素會增肥：
Insulin therapy endeavours to enable patients to replicate the normal physiological insulin response. However, in healthy individuals, insulin first passes through the liver where up to 50% is removed, and endogenous glucose production is suppressed, before entering the peripheral circulation. Treatment with subcutaneous exogenous insulin produces higher levels of peripheral insulin relative to hepatic levels compared with levels in healthy individuals. When good glycaemic control is achieved with exogenous insulin, blood glucose is utilised effectively and any excess energy intake is more likely to be retained and stored as fat. Thus, it is not unexpected that intensive insulin treatment regimens may produce weight gain when initiated in previously poorly controlled patients. This occurs through decreasing glycosuria, and also by insulin-stimulated lipogenesis.
Eating as a defence against hypoglycaemic episodes is a further cause of weight gain in some people with diabetes...... patients who fear hypoglycaemia or experience its symptoms will be likely to eat more, thus avoiding hypoglycaemia, but gaining weight.
In patients transferring to more intensive diabetes treatment regimens, there may be multiple mechanisms for weight gain if energy intake is not reduced or closely managed. It is not surprising, therefore, that weight gain may be seen as an inevitable consequence of diabetes treatment, as the disease progresses over time, whatever therapy is employed to control blood glucose.
控製的好的，一般都是在飲食上做到了嚴格自律。我知道一位一型糖尿病人，12歲時診斷的，他胰島素分泌為0，所以必須打針。很多年10個手指頻繁測血糖被紮得都有老繭了。但是控製得很好，飲食上十分嚴格地低碳水，現在快90歲了，很健康。一點也不胖。
