There is at least one case report of an allergic reaction to oyster mushrooms. According to the report, a mushroom worker experienced chills, fever, joint pain, and skin rashes after exposure to the mushrooms. Symptoms disappeared after a few days.10?
There are other reports of allergic reactions to mushrooms. According to one published case study, prior sensitization to mold allergens might explain severe food reactions to cross-reacting mushroom proteins.11?
If you have a mold allergy, you may experience symptoms of oral allergy syndrome when you consume mushrooms. These symptoms may include itchiness or swelling of the mouth, face, lip, tongue, and throat. If you have an allergy to mold, speak to your healthcare provider before consuming mushrooms.