If you can convince US consular officers in Canada that your ties to Canada are stronger than your ties to China, yes, you can get multiple.
In some countries that US officers have less experience of 3rd country visa, PRC passport holders sometimes can also get the same multiple entry visa that those officers always issue to citizens of other countries. But VO in Canada and Mexico are experienced knowing the PRC's special exception (of single or 2-entry) in the visa reciprocal treaty.
In some countries that US officers have less experience of 3rd country visa, PRC passport holders sometimes can also get the same multiple entry visa that those officers always issue to citizens of other countries. But VO in Canada and Mexico are experienced knowing the PRC's special exception (of single or 2-entry) in the visa reciprocal treaty.