回複：謝謝樓上兩位的答複，請問.....

Yes. Going to Canada means you will abandon your current pending I-485. But you can apply for immigrant visa through consolate process when your PD, which is receipt date of your I-140, becomes current since you have a approved I-140. But I doubt you will come back at that time and start everything from begining if you have a steady job in Canada.