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COVID-19 vaccines and decreased transmission of SARS-CoV-2.
Vitiello A, Ferrara F, Troiano V, La Porta R.Inflammopharmacology. 2021 Oct;29(5):1357-1360. doi: 10.1007/s10787-021-00847-2. Epub 2021 Jul 19.PMID: 34279767 Free PMC article. Review.
A massive COVID-19 vaccination campaign is underway worldwide. Epidemiological data from studies indicate excellent efficacy and safety profile for COVID-19 vaccines. ...
 
 
Omicron variant of SARS-CoV-2: Genomics, transmissibility, and responses to current COVID-19 vaccines.
Araf Y, Akter F, Tang YD, Fatemi R, Parvez MSA, Zheng C, Hossain MG.J Med Virol. 2022 May;94(5):1825-1832. doi: 10.1002/jmv.27588. Epub 2022 Jan 23.PMID: 35023191 Free PMC article. Review.
WHO cautioned that the Omicron variant of SARS-CoV-2 held a very high risk of infection, reigniting anxieties about the economy's recovery from the 2-year pandemic. ...However, there is very limited information on the current situation of the Omicron v …
 
 
What defines an efficacious COVID-19 vaccine? A review of the challenges assessing the clinical efficacy of vaccines against SARS-CoV-2.
Hodgson SH, Mansatta K, Mallett G, Harris V, Emary KRW, Pollard AJ.Lancet Infect Dis. 2021 Feb;21(2):e26-e35. doi: 10.1016/S1473-3099(20)30773-8. Epub 2020 Oct 27.PMID: 33125914 Free PMC article. Review.
An efficacious vaccine is essential to prevent further morbidity and mortality. Although some countries might deploy COVID-19 vaccines on the strength of safety and immunogenicity data alone, the goal of vaccine development is to gain direct evidence of vacci …
 
 
OMICRON (B.1.1.529): A new SARS-CoV-2 variant of concern mounting worldwide fear.
Thakur V, Ratho RK.J Med Virol. 2022 May;94(5):1821-1824. doi: 10.1002/jmv.27541. Epub 2021 Dec 30.PMID: 34936120 Review.
Recent emergence of the SARS-CoV-2 variant as OMICRON has become a global concern. This short note highlights the identification and global spread of OMICRON which has spread over 77 nations by now, which resulted in many hypotheses about its origin and degre …
 
 
COVID-19 Transmission, Current Treatment, and Future Therapeutic Strategies.
Salian VS, Wright JA, Vedell PT, Nair S, Li C, Kandimalla M, Tang X, Carmona Porquera EM, Kalari KR, Kandimalla KK.Mol Pharm. 2021 Mar 1;18(3):754-771. doi: 10.1021/acs.molpharmaceut.0c00608. Epub 2021 Jan 19.PMID: 33464914 Free PMC article. Review.
Although unique in its transmission and virulence, COVID-19 is similar to zoonotic diseases, including other SARS variants (e.g., SARS-CoV) and MERS, in exhibiting severe flu-like symptoms and acute respiratory distress. Even at the molec …
 
 
Lessons learned 1 year after SARS-CoV-2 emergence leading to COVID-19 pandemic.
To KK, Sridhar S, Chiu KH, Hung DL, Li X, Hung IF, Tam AR, Chung TW, Chan JF, Zhang AJ, Cheng VC, Yuen KY.Emerg Microbes Infect. 2021 Dec;10(1):507-535. doi: 10.1080/22221751.2021.1898291.PMID: 33666147 Free PMC article. Review.
Without modern medical management and vaccines, the severity of the Coronavirus Disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV-2) might approach the magnitude of 1 …
 
 
COVID-19: Unmasking Emerging SARS-CoV-2 Variants, Vaccines and Therapeutic Strategies.
Raman R, Patel KJ, Ranjan K.Biomolecules. 2021 Jul 6;11(7):993. doi: 10.3390/biom11070993.PMID: 34356617 Free PMC article. Review.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the etiological agent of the coronavirus disease 2019 (COVID-19) pandemic, which has been a topic of major concern for global human health. The challenge to restrain the C …
 
 
SARS-CoV-2 (Covid-19vaccines structure, mechanisms and effectiveness: A review.
Fathizadeh H, Afshar S, Masoudi MR, Gholizadeh P, Asgharzadeh M, Ganbarov K, Köse ?, Yousefi M, Kafil HS.Int J Biol Macromol. 2021 Oct 1;188:740-750. doi: 10.1016/j.ijbiomac.2021.08.076. Epub 2021 Aug 14.PMID: 34403674 Free PMC article. Review.
The world has been suffering from COVID-19 disease for more than a year, and it still has a high mortality rate. ...In this study, we have reviewed the common platforms of COVID-19 vaccines and tried to present the latest reports on the effectiv …
 
 
Domains and Functions of Spike Protein in Sars-Cov-2 in the Context of Vaccine Design.
Xia X.Viruses. 2021 Jan 14;13(1):109. doi: 10.3390/v13010109.PMID: 33466921 Free PMC article. Review.
The spike protein in SARS-CoV-2 (SARS-2-S) interacts with the human ACE2 receptor to gain entry into a cell to initiate infection. ...Here, I dissect in detail the various domains of SARS-2-S and their functions discovered through …
 
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