| Novel coronavirus (2019-nCoV) | |
|---|---|
Virus classification |
|
| (unranked): | Virus |
| Realm: | Riboviria |
| Phylum: | incertae sedis |
| Order: | Nidovirales |
| Family: | Coronaviridae |
| Genus: | Betacoronavirus |
| Subgenus: | incertae sedis |
| Virus: |
Novel coronavirus (2019-nCoV)
|
 |
|
| Wuhan, China; primary location of the only recorded outbreak | |
| Synonyms | |
|
|
| NCBI genome ID | MN908947 |
|---|---|
| Genome size | 30473 bp |
| Year of completion | 2020 |
Novel coronavirus, denoted 2019-nCoV by the WHO[1][2] and also known as Wuhan coronavirus, Wuhan seafood market pneumonia virus and Wuhan pneumonia,[3] is a positive-sense, single-stranded RNA coronavirus first reported in 2019. The virus was genomically sequenced after nucleic acid testing on a positive patient sample in a patient with pneumonia during the 2019–2020 Wuhan pneumonia outbreak.[4][5][6]
In January 2020, human-to-human transmission was confirmed in Guangdong province, China, according to Zhong Nanshan, head of the health commission team investigating the outbreak.[7] No specific treatment for the new virus is currently available, but existing anti-viralscould be repurposed.[8]
Phylogenetics[edit]
Sequences of Wuhan betacoronavirus show similarities to betacoronaviruses found in bats; however, the virus is genetically distinct from other coronaviruses such as Severe acute respiratory syndrome-related coronavirus (SARS) and Middle East respiratory syndrome-related coronavirus (MERS).[6] Like SARS-CoV, it is a member of Beta-CoV lineage B.[9]
Five genomes of the novel coronavirus have been isolated and reported including BetaCoV/Wuhan/IVDC-HB-01/2019, BetaCoV/Wuhan/IVDC-HB-04/2020, BetaCoV/Wuhan/IVDC-HB-05/2019, BetaCoV/Wuhan/WIV04/2019, and BetaCoV/Wuhan/IPBCAMS-WH-01/2019 from the China CDC National Institute for Viral Disease Control and Prevention, Institute of Pathogen Biology, and Wuhan Jinyintan Hospital.[6][10][11] Its RNA sequence is approximately 30 kbp in length.[6]
References[edit]
- ^ "Surveillance case definitions for human infection with novel coronavirus (nCoV)". www.who.int. Retrieved 21 January 2020.
- ^ "Novel coronavirus (2019-nCoV), Wuhan, China". cdc.gov. 10 January 2020. Retrieved 16 January 2020.
- ^ Zhang, Y.-Z.; et al. (12 January 2020). "Wuhan seafood market pneumonia virus isolate Wuhan-Hu-1, complete genome". GenBank. Bethesda MD. Retrieved 13 January 2020.
- ^ "中國疾病預防控製中心". www.chinacdc.cn. Retrieved 9 January 2020.
- ^ "New-type coronavirus causes pneumonia in Wuhan: expert – Xinhua | English.news.cn". www.xinhuanet.com. Retrieved 9 January 2020.
- ^ a b c d "CoV2020". platform.gisaid.org. Retrieved 12 January2020.
- ^ "China confirms human-to-human transmission of new coronavirus". CBC News. 20 January 2020. Retrieved 21 January 2020.
- ^ "WHO says new China coronavirus could spread, warns hospitals worldwide". Reuters. 14 January 2020. Retrieved 21 January 2020.
- ^ "Phylogeny of SARS-like betacoronaviruses". nextstrain. Retrieved 18 January 2020.
- ^ "Initial genome release of novel coronavirus". Virological. 11 January 2020. Retrieved 12 January 2020.
- ^ "Wuhan seafood market pneumonia virus isolate Wuhan-Hu-1, complete genome". 17 January 2020.
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