You may stay in Fresno for the second night if you want to go to the Sequoia NP. It takes about 1 to 1.5 hours drive.
Your plan should be different than mine because some roads, such as the Tioga road are still closed in Memorial weekend. Check this site for updated road condition: http://www.nps.gov/yose/now/conditions.htm
Days Inn in oakhurst, about 15 miles south of the park
http://www.daysinn.com/DaysInn/control/Booking/search_results?brand_code=DI&p_country=US&p_state=CA&p_city=Oakhurst