宅媽記事
最喜小兒無賴
通常發掘老藥的新功能，可以省去巨額研發及推向臨床費用。 所以很多人致力於研究老藥新用。 Viagra作為處方助性藥物已大火數年，近來又有報道提起它可以減少老年癡呆發病率，男女使用均有效益。查了一下Google和Pubmed，似乎有些過於樂觀
Dr. Desai led the study that found no evidence that Viagra and Cialis reduced the risk of Alzheimer's or related dementias, and Dr. Cheng led the study that found that Viagra was associated with a reduced risk of Alzheimer's disease. These responses have been lightly edited for length and clarity.Dec 19, 2022
Viagra could slash risk of Alzheimer’s disease by 60%: study
Viagra could cut the risk of Alzheimer’s disease by 60%, according to a new study.
Researchers from Mount Sinai Medical Center in New York found that Viagra (sildenafil), a drug most commonly used to treat erectile dysfunction, blocks an enzyme found in the brains of those who suffer from the disease.
The study looked at more than 27,000 people over 65, comparing half of the participants who had been prescribed sildenafil with half who had not. Findings showed that Viagra suppresses a protein called PDE5.
In Alzheimer’s patients, PDE5 is “significantly increased” in the part of the brain that manages memory.
“We found sildenafil was significantly associated with a 60% lower risk of developing Alzheimer’s disease,” study author Xingyue Huo told The Sun.
Original article：
