Yes, as long as you still work in the field after filing 485.

CIS may send a RFE to request employment verifiation letter. But 140 will not get revoked.

see below:
---Can an approved I-140 expire? If so, after how long? Thanks in advance.

Attorney Murthy : By law, an I-140 petition is valid forever! That means, even after 20 years or 50 years, though after a certain length of time, it may not be as relevant since the person has to show that the employer still needs the person for that job, etc.