Make sure there is no spreading and metastasis
If there is no metastasis and spreading, try to do surgery.If there is spreading and metastasis, do not have the patient to be operation. Try to do immunotherapy or gene therapy. If it is possible, do cancer foci direct injection of recombinant lentiviral particles. These lentiviral viruses producing CDC6 shRNA, p16, PTEN, p53 and Gankyrin shRNA. The recombinant viruses can infect cancer cellls and make gene transduction of cancer cells to have cancer cell progression to be inhibited.To have such kind of therapy, there is low side effect or no side effect.