2000 Accord EX V6 199,000 miles.
Engine run rough ( the car was shaking a bit ) with code P0080,P0200,P0300,P0305 and P0306.
P0300,P0305 and P0306 are related to engine misfire.
The bad one could be identified by disconnecting wire to ignition coil while it's running.
(Please note: 2000 V6 is ignition coil but spark plug wire ).
The good one: engine runs the worse while the wire is disconnected
The bad one: engine run unchange. ( there are how-to videos on youtube).
The number 2 of ignition coil was bad. The part is from ebay.
Actually, this is the second time. The first time was about 2 months ago.
Back then, I was wondering if all ignition coils should be replaced given one of them was bad. Now I am going to replace the reminding ones.