205 From the bottom of one’s heart

(PW) with great feeling, sincerely

My sister thanked me from the bottom of her heart for saving her dog’s life.

(wiki)  idiomatic, In earnest; sincerely; with one's full feeling.

He told her how much he loved her, and he meant it from the bottom of his heart.

(your) Most sincerely, unreservedly

For example, I want to thank all of my supporters from the bottom of my heart, or She wished, from the bottom of her heart, that her daughter would get well. In English this term appeared in the Anglican Book of Common Prayer's Communion service (1545): “If one ... be content to forgive from the bottom of his heart”; in Latin it dates back to Virgil.

(dictionary) with complete sincerity

Also, from one's heart, from the heart.

(free)

With the deepest appreciation; most sincerely.